The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif
about
The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamilyStructural and mechanistic analysis oftrans-3-chloroacrylic acid dehalogenase activityKinetic and Structural Characterization of a Heterohexamer 4-Oxalocrotonate Tautomerase from Chloroflexus aurantiacus J-10-fl: Implications for Functional and Structural Diversity in the Tautomerase Superfamily,Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family membersCrystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanismsKinetic, Crystallographic, and Mechanistic Characterization of TomN: Elucidation of a Function for a 4-Oxalocrotonate Tautomerase Homologue in the Tomaymycin Biosynthetic PathwayKinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase ActivitiesStructural and kinetic characterization of two 4-oxalocrotonate tautomerases in Methylibium petroleiphilum strain PM1Evidence for the formation of an enamine species during aldol and Michael-type addition reactions promiscuously catalyzed by 4-oxalocrotonate tautomeraseKinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactionsThe S. aureus 4-oxalocrotonate tautomerase SAR1376 enhances immune responses when fused to several antigens.Identification and characterization of new family members in the tautomerase superfamily: analysis and implicationsIntegrase-directed recovery of functional genes from genomic librariesReaction mechanism of cis-3-chloroacrylic acid dehalogenase: a theoretical studyThe chemical versatility of the beta-alpha-beta fold: catalytic promiscuity and divergent evolution in the tautomerase superfamily.A persistent pesticide residue and the unusual catalytic proficiency of a dehalogenating enzymeInactivation of tautomerase activity of macrophage migration inhibitory factor by sulforaphane: a potential biomarker for anti-inflammatory interventionMutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4-Oxalocrotonate Tautomerase More Effectively than Distant Mutations.Engineering a Promiscuous Tautomerase into a More Efficient Aldolase for Self-Condensations of Linear Aliphatic Aldehydes.Catalytic mechanism of 4-oxalocrotonate tautomerase: significances of protein-protein interactions on proton transfer pathways.Phenylpyruvate tautomerase activity of trans-3-chloroacrylic acid dehalogenase: evidence for an enol intermediate in the dehalogenase reaction?Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural consequences of the L8R mutation in 4-oxalocrotonate tautomeraseCritical role of substrate conformational change in the proton transfer process catalyzed by 4-oxalocrotonate tautomerase.Recent advances in the study of enzyme promiscuity in the tautomerase superfamily.Fluoro amino acids: a rarity in nature, yet a prospect for protein engineering.Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases.Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction.Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase.Characterization of Cg10062 from Corynebacterium glutamicum: implications for the evolution of cis-3-chloroacrylic acid dehalogenase activity in the tautomerase superfamily.Inactivation of Cg10062, a cis-3-chloroacrylic acid dehalogenase homologue in Corynebacterium glutamicum, by (R)- and (S)-oxirane-2-carboxylate: analysis and implications.Promiscuous catalysis of asymmetric Michael-type additions of linear aldehydes to β-nitrostyrene by the proline-based enzyme 4-oxalocrotonate tautomerase.Mechanistic characterization of a bacterial malonate semialdehyde decarboxylase: identification of a new activity on the tautomerase superfamily.A global view of structure-function relationships in the tautomerase superfamily.Enzyme kinetics and transport in a system crowded by mobile macromolecules.Inter- and intramolecular aldol reactions promiscuously catalyzed by a proline-based tautomerase.Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes.
P2860
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P2860
The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif
description
2002 nî lūn-bûn
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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@ast
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@en
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@nl
type
label
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@ast
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@en
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@nl
altLabel
The 4-oxalocrotonate tautomera ...... using a β–α–β structural motif
@en
prefLabel
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@ast
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@en
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@nl
P1476
The 4-oxalocrotonate tautomera ...... ta-alpha-beta structural motif
@en
The 4-oxalocrotonate tautomera ...... using a β–α–β structural motif
@en
P2093
Christian P Whitman
P356
10.1016/S0003-9861(02)00052-8
P407
P577
2002-06-01T00:00:00Z