Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors
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Kallmann syndrome: mutations in the genes encoding prokineticin-2 and prokineticin receptor-2The endocrine-gland-derived VEGF homologue Bv8 promotes angiogenesis in the testis: Localization of Bv8 receptors to endothelial cellsThe AVIT protein family. Secreted cysteine-rich vertebrate proteins with diverse functionsPROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activityNociceptive sensitization by the secretory protein Bv8The role of the prokineticin 2 pathway in human reproduction: evidence from the study of human and murine gene mutationsModeling of human prokineticin receptors: interactions with novel small-molecule binders and potential off-target drugsDiscovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadismThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsThe prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1.Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake.Identification and characterization of regulator of G protein signaling 4 (RGS4) as a novel inhibitor of tubulogenesis: RGS4 inhibits mitogen-activated protein kinases and vascular endothelial growth factor signaling.The role of prokineticins in the pathogenesis of hypogonadotropic hypogonadismAbnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis.Disease-causing mutation in PKR2 receptor reveals a critical role of positive charges in the second intracellular loop for G-protein coupling and receptor trafficking.Bv8, the amphibian homologue of the mammalian prokineticins, modulates ingestive behaviour in rats.Prokineticin receptor 1 as a novel suppressor of preadipocyte proliferation and differentiation to control obesity.New insights into endothelial diversity.The puzzles of the prokineticin 2 pathway in human reproductionProkineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei.Prokineticin 2 is an endangering mediator of cerebral ischemic injuryEvidence of the importance of the first intracellular loop of prokineticin receptor 2 in receptor function.Role of Endocrine Gland-Derived Vascular Endothelial Growth Factor (EG-VEGF) and Its Receptors in Adrenocortical TumorsProkineticin 2 and circadian clock output.Orphan GPCRs and neuromodulation.Prokineticin-2 is associated with metabolic syndrome in a middle-aged and elderly Chinese population.Olfactory bulb hypoplasia in Prokr2 null mice stems from defective neuronal progenitor migration and differentiation.Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progressionExpression of prokineticin-receptor2(PK-R2) is a new prognostic factor in human colorectal cancer.Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem.The prokineticins: a novel pair of regulatory peptides.Potential roles of the prokineticins in reproductionModulators of pain: Bv8 and prokineticins.PROK2/PROKR2 Signaling and Kallmann Syndrome.Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain.G-protein-coupled receptor agonist BV8/prokineticin-2 and STAT3 protein form a feed-forward loop in both normal and malignant myeloid cells.Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development.Ontogenesis of gonadotropin-releasing hormone neurons: a model for hypothalamic neuroendocrine cell development.
P2860
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P2860
Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Isolation and identification o ...... an G-protein-coupled receptors
@ast
Isolation and identification o ...... an G-protein-coupled receptors
@en
Isolation and identification o ...... an G-protein-coupled receptors
@nl
type
label
Isolation and identification o ...... an G-protein-coupled receptors
@ast
Isolation and identification o ...... an G-protein-coupled receptors
@en
Isolation and identification o ...... an G-protein-coupled receptors
@nl
prefLabel
Isolation and identification o ...... an G-protein-coupled receptors
@ast
Isolation and identification o ...... an G-protein-coupled receptors
@en
Isolation and identification o ...... an G-protein-coupled receptors
@nl
P2093
P3181
P1476
Isolation and identification o ...... an G-protein-coupled receptors
@en
P2093
Haruo Onda
Masahiko Fujino
Masato Suenaga
Michiko Abe
Nobuhiro Inatomi
Satoshi Kumano
Shoji Fukusumi
Shuji Hinuma
Takao Yamada
Takuya Watanabe
P304
P3181
P356
10.1016/S0006-291X(02)00239-5
P407
P577
2002-04-26T00:00:00Z