Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel
about
A discrete alcohol pocket involved in GIRK channel activationKir3 channel signaling complexes: focus on opioid receptor signalingCrystal structure of a Kir3.1-prokaryotic Kir channel chimeraA Structural Determinant for the Control of PIP2 Sensitivity in G Protein-gated Inward Rectifier K+ ChannelsIdentification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinaseFour and a half LIM protein 1C (FHL1C): a binding partner for voltage-gated potassium channel K(v1.5).NMR analyses of the Gbetagamma binding and conformational rearrangements of the cytoplasmic pore of G protein-activated inwardly rectifying potassium channel 1 (GIRK1).The role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels.Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunitsA Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding.Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids.Molecular mechanism underlying ethanol activation of G-protein-gated inwardly rectifying potassium channels.Supramolecular assemblies and localized regulation of voltage-gated ion channels.A comprehensive guide to the ROMK potassium channel: form and function in health and disease.N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer.Kir3 channel ontogeny - the role of Gβγ subunits in channel assembly and trafficking.K(+) channels: function-structural overview.New insights into the therapeutic potential of Girk channels.Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics.G protein {beta}{gamma} gating confers volatile anesthetic inhibition to Kir3 channels.betaL-betaM loop in the C-terminal domain of G protein-activated inwardly rectifying K(+) channels is important for G(betagamma) subunit activation.A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels.Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma.Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels.Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes.Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus.Emerging role(s) of G-protein alpha-subunits in the gating of GIRKs.G protein modulation of K2P potassium channel TASK-2 : a role of basic residues in the C terminus domain.
P2860
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P2860
Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@ast
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@en
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@nl
type
label
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@ast
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@en
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@nl
altLabel
Mapping the Gβγ-binding Sites ...... G Protein-activated K+Channel
@en
prefLabel
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@ast
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@en
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@nl
P2093
P2860
P356
P1476
Mapping the Gbetagamma-binding ...... G protein-activated K+ channel
@en
P2093
Bibiane Frohnwieser-Steinecke
Carmen Mullner
Carmen W Dessauer
Dalia Varon
Ida Rishal
Tatiana Ivanina
P2860
P304
29174-29183
P356
10.1074/JBC.M304518200
P407
P577
2003-05-12T00:00:00Z