Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542
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Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signalingRequirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells.Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARAInterfering with TGFbeta-induced Smad3 nuclear accumulation differentially affects TGFbeta-dependent gene expressionA Novel High-Throughput 3D Screening System for EMT Inhibitors: A Pilot Screening Discovered the EMT Inhibitory Activity of CDK2 Inhibitor SU9516Multi-lineage MSC differentiation via engineered morphogen fields.TGFbeta1 stimulates the over-production of white matter astrocytes from precursors of the "brain marrow" in a rodent model of neonatal encephalopathyActivation of the TGFβ pathway impairs endothelial to haematopoietic transition.Complexities of TGF-β targeted cancer therapy.Transcriptional induction of Smurf2 ubiquitin ligase by TGF-betaTGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4Activation of protein serine/threonine phosphatase PP2Cα efficiently prevents liver fibrosisEfficient generation of fully reprogrammed human iPS cells via polycistronic retroviral vector and a new cocktail of chemical compoundsOral administration of GW788388, an inhibitor of transforming growth factor beta signaling, prevents heart fibrosis in Chagas diseaseIn vitro modeling of paraxial mesodermal progenitors derived from induced pluripotent stem cellsDifferential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer ModelSignaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell developmentA possible role of acrolein in diabetic retinopathy: involvement of a VEGF/TGFβ signaling pathway of the retinal pigment epithelium in hyperglycemiaDual function of TGFβ in lens epithelial cell fate: implications for secondary cataract.Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone.Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.A keratinocyte hypermotility/growth-arrest response involving laminin 5 and p16INK4A activated in wound healing and senescence.Cx43 mediates TGF-beta signaling through competitive Smads binding to microtubules.Structural basis for potency differences between GDF8 and GDF11.Low concentrations of transforming growth factor-beta-1 induce tubulogenesis in cultured mammary epithelial cells.Inhibition of ALK5 signaling induces physeal dysplasia in rats.Transforming growth factor: beta signaling is essential for limb regeneration in axolotlsActivator protein-1 and smad proteins synergistically regulate human follicle-stimulating hormone beta-promoter activityLiver cancer-derived hepatitis C virus core proteins shift TGF-beta responses from tumor suppression to epithelial-mesenchymal transitionComplete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathwayStimulation of chondrogenic differentiation of adult human bone marrow-derived stromal cells by a moderate-strength static magnetic field.The transcriptional regulators TAZ and YAP direct transforming growth factor β-induced tumorigenic phenotypes in breast cancer cells.Suppression of TGFβ-induced epithelial-mesenchymal transition like phenotype by a PIAS1 regulated sumoylation pathway in NMuMG epithelial cells.Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells.Altered shear stress stimulates upregulation of endothelial VCAM-1 and ICAM-1 in a BMP-4- and TGF-beta1-dependent pathwayCorrect anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer.TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.Nodal signaling regulates the bone morphogenic protein pluripotency pathway in mouse embryonic stem cellsNeuropilin-2 expression promotes TGF-β1-mediated epithelial to mesenchymal transition in colorectal cancer cells.The notch and TGF-β signaling pathways contribute to the aggressiveness of clear cell renal cell carcinoma.
P2860
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P2860
Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@ast
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@en
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@nl
type
label
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@ast
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@en
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@nl
prefLabel
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@ast
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@en
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@nl
P2093
P3181
P356
P1476
Inhibition of transforming gro ...... tor kinase activity: SB-431542
@en
P2093
E Grygielko
J Bomberger
J F Callahan
J Fornwald
N J Laping
P3181
P356
10.1124/MOL.62.1.58
P407
P577
2002-07-01T00:00:00Z