Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells
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DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptorNMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomersPIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunitThe interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaBInteraction of protein inhibitor of activated STAT 2 (PIAS2) with receptor of activated C kinase 1, RACK1Principles of interleukin (IL)-6-type cytokine signalling and its regulationMembers of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activityTranscription factor Sp3 is silenced through SUMO modification by PIAS1Protein inhibitor of activated STAT Y (PIASy) and a splice variant lacking exon 6 enhance sumoylation but are not essential for embryogenesis and adult lifePIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodiesLoss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expressionActivation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylationInduction of apoptosis by protein inhibitor of activated Stat1 through c-Jun NH2-terminal kinase activationPIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcriptionPIAS3 (protein inhibitor of activated STAT-3) modulates the transcriptional activation mediated by the nuclear receptor coactivator TIF2Regulation of gene-activation pathways by PIAS proteins in the immune systemSignal transducer and activator of transcription 5A/B in prostate and breast cancersUbiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4Transforming growth factor-beta1 attenuates expression of both the progesterone receptor and Dickkopf in differentiated human endometrial stromal cellsThe Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer.Negative regulation of NF-kappaB signaling by PIAS1.The DEAD-box protein DP103 (Ddx20 or Gemin-3) represses orphan nuclear receptor activity via SUMO modification.Phosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1.Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1.Identification of a structural motif in the tumor-suppressive protein GRIM-19 required for its antitumor activityCytokine-induced tumor suppressors: a GRIM storyPIASgamma represses the transcriptional activation induced by the nuclear receptor Nurr1.The SAP motif and C-terminal RS- and RD/E-rich region influences the sub-nuclear localization of Acinus isoforms.Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cellsPIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleusTranscriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3).Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT.MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.Gene expression profiling in the myelodysplastic syndromes.
P2860
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P2860
Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@ast
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@en
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@nl
type
label
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@ast
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@en
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@nl
prefLabel
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@ast
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@en
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
Distinct effects of PIAS prote ...... ation in prostate cancer cells
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1204489
P407
P577
2001-06-28T00:00:00Z
P5875
P6179
1000707609