Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction
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Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105Recombinant bactericidal/permeability-increasing protein rBPI21 protects against pneumococcal diseaseInnate Immune Response in Brain, NF-Kappa B Signaling and CystatinsCrystal structures of human MD-2 and its complex with antiendotoxic lipid IVaCrystal structure of soluble MD-1 and its interaction with lipid IVaLocation, location, location: is membrane partitioning everything when it comes to innate immune activation?A coding mutation within the first exon of the human MD-2 gene results in decreased lipopolysaccharide-induced signalingSignal transduction by the lipopolysaccharide receptor, Toll-like receptor-4The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 bindingTemperature-induced changes in the lipopolysaccharide of Yersinia pestis affect plasminogen activation by the pla surface proteaseInvited review: Breaking barriers--attack on innate immune defences by omptin surface proteases of enterobacterial pathogens.Necessity of oligonucleotide aggregation for toll-like receptor 9 activation.Synthetic toll-like receptor 4 agonists stimulate innate resistance to infectious challenge.Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction.N-linked glycosylation at Asn3 and the positively charged residues within the amino-terminal domain of the c1 inhibitor are required for interaction of the C1 Inhibitor with Salmonella enterica serovar typhimurium lipopolysaccharide and lipid A.The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal diseaseRegulation of cellular caveolin-1 protein expression in murine macrophages by microbial products.Involvement of TLR2 and TLR4 in cell responses to Rickettsia akariß-adrenergic stimulation increases macrophage CD14 expression and E. coli phagocytosis through PKA signaling mechanismsA peptide antagonist of the TLR4-MD2 interaction.Endotoxin recognition: in fish or not in fish?Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory ResponseThe SCHOOL of nature: III. From mechanistic understanding to novel therapiesIdentification of a novel human MD-2 splice variant that negatively regulates Lipopolysaccharide-induced TLR4 signalingImmune modulation by different types of β2→1-fructans is toll-like receptor dependentNovel drugs targeting Toll-like receptors for antiviral therapy.Alternatively spliced myeloid differentiation protein-2 inhibits TLR4-mediated lung inflammation.Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.SMOCs: supramolecular organizing centres that control innate immunity.Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm BirthModulating LPS signal transduction at the LPS receptor complex with synthetic Lipid A analoguesAspects of innate immunity and Parkinson's disease.Toll-like receptor 2 is required for LPS-induced Toll-like receptor 4 signaling and inhibition of ion transport in renal thick ascending limb.Activation of Human Toll-like Receptor 4 (TLR4)·Myeloid Differentiation Factor 2 (MD-2) by Hypoacylated Lipopolysaccharide from a Clinical Isolate of Burkholderia cenocepaciaExpression of toll-like receptor 4 and MD-2 gene and protein in Kupffer cells after ischemia-reperfusion in rat liver graft.Inflammation--a new therapeutic target in pneumonia.Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.Lipopolysaccharide heterogeneity: innate host responses to bacterial modification of lipid a structure.R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88A comprehensive map of the toll-like receptor signaling network.
P2860
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P2860
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Lysines 128 and 132 enable lip ...... gation and signal transduction
@ast
Lysines 128 and 132 enable lip ...... gation and signal transduction
@en
Lysines 128 and 132 enable lip ...... gation and signal transduction
@nl
type
label
Lysines 128 and 132 enable lip ...... gation and signal transduction
@ast
Lysines 128 and 132 enable lip ...... gation and signal transduction
@en
Lysines 128 and 132 enable lip ...... gation and signal transduction
@nl
prefLabel
Lysines 128 and 132 enable lip ...... gation and signal transduction
@ast
Lysines 128 and 132 enable lip ...... gation and signal transduction
@en
Lysines 128 and 132 enable lip ...... gation and signal transduction
@nl
P2093
P356
P1476
Lysines 128 and 132 enable lip ...... gation and signal transduction
@en
P2093
Alberto Visintin
Brian G Monks
Douglas T Golenbock
P304
P356
10.1074/JBC.M306802200
P407
P577
2003-11-28T00:00:00Z