Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin
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Galectins in epithelial functionsCyclin-dependent kinase inhibitors and JNK act as molecular switches, regulating the choice between growth arrest and apoptosis induced by galectin-8Galectins: structure, function and therapeutic potentialGalectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin.Alternative splicing in osteoclasts and Paget's disease of bone.Role of galectins in re-epithelialization of wounds.The mammalian lectin galectin-8 induces RANKL expression, osteoclastogenesis, and bone mass reduction in mice.A C. elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration.Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signalingGalectin-8 induces apoptosis in Jurkat T cells by phosphatidic acid-mediated ERK1/2 activation supported by protein kinase A down-regulation.The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreadingGene expression profile of lymphatic endothelial cells.Galectin-8: a matricellular lectin with key roles in angiogenesis.Galectin-3-induced cell spreading and motility relies on distinct signaling mechanisms compared to fibronectin.Rapamycin inhibits fibronectin-induced migration of the human arterial smooth muscle line (E47) through the mammalian target of rapamycin.beta1-integrin mediates asbestos-induced phosphorylation of AKT and ERK1/2 in a rat pleural mesothelial cell line.Stable and high expression of Galectin-8 tightly controls metastatic progression of prostate cancerA dual role for the βPS integrin myospheroid in mediating Drosophila embryonic macrophage migration.Epigenetic regulation of galectin-3 expression by β1 integrins promotes cell adhesion and migration.Human platelets express and are activated by galectin-8.Extracellular matrix proteins modulate endocytosis of the insulin receptor.Intestinal ribosomal p70(S6K) signaling is increased in piglet rotavirus enteritis.Excessive secretion of IL-8 by skeletal muscle in type 2 diabetes impairs tube growth: potential role of PI3K and the Tie2 receptor.It depends on the hinge: a structure-functional analysis of galectin-8, a tandem-repeat type lectin.Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in MDCK cells.Expression profiling of radiation-induced genes in radiodermatitis of hairless mice.Knockdown of cysteine-rich 61 inhibits proliferation, migration, and invasiveness of prostate carcinoma PC-3 cells
P2860
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P2860
Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@ast
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@en
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@nl
type
label
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@ast
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@en
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@nl
prefLabel
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@ast
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@en
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@nl
P2093
P356
P1476
Sustained induction of ERK, pr ...... galectin-8, a mammalian lectin
@en
P2093
Alexander D Bershadsky
Denise Ronen
Yehiel Zick
Yifat Levy
P304
P356
10.1074/JBC.M207380200
P407
P577
2003-04-18T00:00:00Z