PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
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The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminusRole of PDZK1 in membrane expression of renal brush border ion exchangers.Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase IILarge-scale phosphoproteomic analysis of membrane proteins in renal proximal and distal tubuleMolecular mechanisms and regulation of urinary acidificationRegulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factorsDefective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient miceTranscriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formationLongitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null miceCytosolic COOH terminus of the peptide transporter PEPT2 is involved in apical membrane localization of the protein.Sip1, the Drosophila orthologue of EBP50/NHERF1, functions with the sterile 20 family kinase Slik to regulate Moesin activity.NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol.Regulation of SR-BI protein levels by phosphorylation of its associated protein, PDZK1.Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.CFTR chloride channel in the apical compartments: spatiotemporal coupling to its interacting partners.Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney.Intrinsic disorder in scaffold proteins: getting more from lessNormal hepatic cell surface localization of the high density lipoprotein receptor, scavenger receptor class B, type I, depends on all four PDZ domains of PDZK1.Identification of novel tissue-specific genes by analysis of microarray databases: a human and mouse model.Interstitial calcinosis in renal papillae of genetically engineered mouse models: relation to Randall's plaquesRole of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters.Novel NaPi-IIc mutations causing HHRH and idiopathic hypercalciuria in several unrelated families: long-term follow-up in one kindred.PDZ interactions and proximal tubular phosphate reabsorption.Regulation of ion transport by the NHERF family of PDZ proteins.PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes.Mutation conferring apical-targeting motif on AE1 exchanger causes autosomal dominant distal RTA.NaPi-IIa and interacting partners.The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.Beyond the brush border: NHERF4 blazes new NHERF turf.Recent advances in renal phosphate transport.Getting under the skin: the immunogenetics of psoriasis.Endocrine and metabolic regulation of renal drug transporters.Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cellsContributions of phosphorylation to regulation of OCTN2 uptake of carnitine are minimal in BeWo cells.The emerging role of PDZ adapter proteins for regulation of intestinal ion transport.Inorganic phosphate modulates the expression of the NaPi-2a transporter in the trans-Golgi network and the interaction with PIST in the proximal tubule.Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid systemThe calcineurin homologous protein-1 increases Na(+)/H(+) -exchanger 3 trafficking via ezrin phosphorylationLow-salt diet and cyclosporine nephrotoxicity: changes in kidney cell metabolism.The scaffold protein PDZK1 undergoes a head-to-tail intramolecular association that negatively regulates its interaction with EBP50.
P2860
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P2860
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@ast
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@en
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
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type
label
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@ast
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@en
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@nl
prefLabel
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@ast
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@en
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@nl
P2093
P1433
P1476
PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
@en
P2093
Akira Tsuji
Andrea Gantenbein
Desa Bacic
Edward Manser
Heini Murer
Jürg Biber
Luc A Sabourin
Patrik Forrer
Sandra Pribanic
Serge M Gisler
P304
P356
10.1046/J.1523-1755.2003.00266.X
P407
P577
2003-11-01T00:00:00Z
P5875
P6179
1020435366