Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates
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The generation and function of soluble apoE receptors in the CNSFCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosisThe low density lipoprotein receptor-1, LRP1, interacts with the human frizzled-1 (HFz1) and down-regulates the canonical Wnt signaling pathwayA large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complexDisabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptorA secreted soluble form of ApoE receptor 2 acts as a dominant-negative receptor and inhibits Reelin signalingApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseCanonical and Non-canonical Reelin SignalingImpaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's diseaseThe fast-recycling receptor Megalin defines the apical recycling pathway of epithelial cells.Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrierMegalin/LRP2 expression is induced by peroxisome proliferator-activated receptor -alpha and -gamma: implications for PPARs' roles in renal functionRoles of low-density lipoprotein receptor-related protein 1 in tumorsApolipoprotein E (apoE) isoforms differentially induce nitric oxide production in endothelial cellsNormal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemiaPKB/Akt partners with Dab2 in albumin endocytosisRole of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer diseaseCentral role for PICALM in amyloid-β blood-brain barrier transcytosis and clearanceHuman rhinovirus type 2 is internalized by clathrin-mediated endocytosisRegulation of Rac1 activation by the low density lipoprotein receptor-related proteinIdentification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathwayLow density lipoprotein (LDL) receptor-related protein 1B impairs urokinase receptor regeneration on the cell surface and inhibits cell migration.Low-density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer's amyloid β-peptide elimination from the brainNuclear targeting by the growth factor midkine.Fyn tyrosine kinase increases Apolipoprotein E Receptor 2 levels and phosphorylation.Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegenerationPremature ligand-receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1Amyloid-Beta interaction with mitochondriaClearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.Modulation of beta-amyloid precursor protein trafficking and processing by the low density lipoprotein receptor family.Specific deletion of LDL receptor-related protein on macrophages has skewed in vivo effects on cytokine production by invariant natural killer T cells.Cholesterol metabolism and homeostasis in the brainNeurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's diseaseThe apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.LRP and Alzheimer's disease.
P2860
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P2860
Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates
description
2001 nî lūn-bûn
@nan
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Differential functions of memb ...... eir distinct endocytosis rates
@ast
Differential functions of memb ...... eir distinct endocytosis rates
@en
Differential functions of memb ...... eir distinct endocytosis rates
@nl
type
label
Differential functions of memb ...... eir distinct endocytosis rates
@ast
Differential functions of memb ...... eir distinct endocytosis rates
@en
Differential functions of memb ...... eir distinct endocytosis rates
@nl
prefLabel
Differential functions of memb ...... eir distinct endocytosis rates
@ast
Differential functions of memb ...... eir distinct endocytosis rates
@en
Differential functions of memb ...... eir distinct endocytosis rates
@nl
P2093
P2860
P3181
P356
P1476
Differential functions of memb ...... eir distinct endocytosis rates
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M101589200
P407
P577
2001-05-25T00:00:00Z