The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC
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Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemiaNucleophosmin interacts with and inhibits the catalytic function of eukaryotic initiation factor 2 kinase PKRRAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infectionImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionHost-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 proteinThe Fanconi anemia pathway and ubiquitinFanconi anemia proteins and their interacting partners: a molecular puzzleDirect inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytesGenetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Bone marrow cell transcripts from Fanconi anaemia patients reveal in vivo alterations in mitochondrial, redox and DNA repair pathways.West Nile virus infection does not induce PKR activation in rodent cells.GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines.Fanconi anaemia and leukaemia - clinical and molecular aspects.Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1.TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.The protein activator of protein kinase R, PACT/RAX, negatively regulates protein kinase R during mouse anterior pituitary development.Loss of Fancc Impairs Antibody-Secreting Cell Differentiation in Mice through Deregulating the Wnt Signaling Pathway.Heat shock proteins and regulatory T cellsHeat shock proteins: essential proteins for apoptosis regulation.Oxidative stress in Fanconi anemia hematopoiesis and disease progression.FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages.TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.TNF-α signaling in Fanconi anemia.Stress and DNA repair biology of the Fanconi anemia pathwayToll-like receptor signaling in hematopoietic homeostasis and the pathogenesis of hematologic diseases.Targeting Hsp70: A possible therapy for cancer.Emerging functions of the Fanconi anemia pathway at a glance.The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells.Persistent borna disease virus infection confers instability of HSP70 mRNA in glial cells during heat stress.Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic ApproachEx vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.Inflammatory reactive oxygen species-mediated hemopoietic suppression in Fancc-deficient miceHuman gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN PKR-induced apoptosis.GST genotype may modify clinical phenotype in patients with Fanconi anaemia.Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway.Hsp70: A Cancer Target Inside and Outside the Cell.Recent advances in understanding hematopoiesis in Fanconi Anemia.Hsp70 and gama-Semino protein as possible prognostic marker of prostate cancer.
P2860
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P2860
The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@ast
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@en
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@nl
type
label
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@ast
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@en
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@nl
prefLabel
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@ast
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@en
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@nl
P2093
P2860
P356
P1476
The anti-apoptotic function of ...... Fanconi anemia protein, FANCC
@en
P2093
Grover C Bagby
Qishen Pang
Tara Koretsky
Tracy A Christianson
Winifred Keeble
P2860
P304
P356
10.1074/JBC.M209386200
P407
P577
2002-12-20T00:00:00Z