A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer
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BRCA1 inhibition of telomerase activity in cultured cellsNFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytesNFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cellsUse of adenoviral E1A protein to analyze K18 promoter deregulation in colon carcinoma cells discloses a role for CtBP1 and BRCA1.Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneBRCA1, a 'complex' protein involved in the maintenance of genomic stabilityRoles of N-Myc and STAT interactor in cancer: From initiation to disseminationBRCA1 associates with processive RNA polymerase IIBovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activityBRCA1 and Oxidative StressBRCA1 interacts with Smad3 and regulates Smad3-mediated TGF-beta signaling during oxidative stress responsesMYC and the control of DNA replication.N-Myc interactor inhibits prototype foamy virus by sequestering viral Tas protein in the cytoplasm.Wild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-cateninRegulation of the human catalytic subunit of telomerase (hTERT).microRNA-29 negatively regulates EMT regulator N-myc interactor in breast cancerMYC in breast tumor progressionLoss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signaling.MYC and Breast Cancer.Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling.Transcriptional changes associated with breast cancer occur as normal human mammary epithelial cells overcome senescence barriers and become immortalized.High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis.MYCbase: a database of functional sites and biochemical properties of Myc in both normal and cancer cells.NMI mediates transcription-independent ARF regulation in response to cellular stressesTelomerase as a useful target in cancer fighting-the breast cancer case.Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.An unbiased in vivo screen reveals multiple transcription factors that control HPV E6-regulated hTERT in keratinocytes.NMI promotes hepatocellular carcinoma progression via BDKRB2 and MAPK/ERK pathway.Human telomerase expression regulation.Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis.Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells.The BRCA1 COOH-terminal region acts as an RNA polymerase II carboxyl-terminal domain kinase inhibitor that modulates p21WAF1/CIP1 expression.The 2,5 oligoadenylate synthetase/RNaseL pathway is a novel effector of BRCA1- and interferon-gamma-mediated apoptosis.NMI inhibits cancer stem cell traits by downregulating hTERT in breast cancer.The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription.Thromboxane A2 receptor (TBXA2R) is a potent survival factor for triple negative breast cancers (TNBCs).NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury.Interferon activates promoter of Nmi gene via interferon regulator factor-1.NMI and EMT.
P2860
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P2860
A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@ast
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@en
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@nl
type
label
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@ast
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@en
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@nl
prefLabel
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@ast
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@en
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@nl
P2093
P2860
P3181
P356
P1476
A novel tricomplex of BRCA1, N ...... oter activity in breast cancer
@en
P2093
Hava Avraham
Tae-Hee Lee
P2860
P304
P3181
P356
10.1074/JBC.M112231200
P407
P577
2002-06-07T00:00:00Z