The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility
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Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22The urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyGlobal gene expression analysis identifies PDEF transcriptional networks regulating cell migration during cancer progressionNuclear translocation of urokinase-type plasminogen activatorNon-muscle alpha-actinin-4 interacts with plasminogen activator inhibitor type-1 (PAI-1).In silico docking of urokinase plasminogen activator and integrins.Breast cancer and metabolic syndrome linked through the plasminogen activator inhibitor-1 cyclePleiotropic functions of plasminogen activator inhibitor-1.The molecular basis for anti-proteolytic and non-proteolytic functions of plasminogen activator inhibitor type-1: roles of the reactive centre loop, the shutter region, the flexible joint region and the small serpin fragment.Urokinase and its receptors in chronic kidney disease.Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers.SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA.Membrane associated proteases and their inhibitors in tumour angiogenesis.Monomer dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assembliesIntraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins.uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.The urokinase plasminogen activator receptor promotes efferocytosis of apoptotic cells.Urokinase receptor orchestrates the plasminogen system in airway epithelial cell function.Prostate cancer cell surface-associated keratin 8 and its implications for enhanced plasmin activity.Plasminogen activator inhibitors regulate cell adhesion through a uPAR-dependent mechanism.A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor.The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style.Parathyroid hormone-related protein regulates tumor-relevant genes in breast cancer cells.An uncleavable uPAR mutant allows dissection of signaling pathways in uPA-dependent cell migration.The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells.Spontaneous lung and lymph node metastasis in transgenic breast cancer is independent of the urokinase receptor uPAR.A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells.Inhibition of choroidal neovascularization in rats by the urokinase-derived peptide A6.ARF6-dependent activation of ERK and Rac1 modulates epithelial tubule developmentSerine proteases, inhibitors and receptors in renal fibrosis.uPA-uPAR molecular complex is involved in cell signaling during neuronal migration and neuritogenesis.Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression.HGF Modulates Actin Cytoskeleton Remodeling and Contraction in Testicular Myoid Cells.
P2860
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P2860
The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@ast
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@en
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@nl
type
label
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@ast
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@en
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@nl
prefLabel
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@ast
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@en
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@nl
P2860
P356
P1433
P1476
The urokinase plasminogen acti ...... cytoskeleton and cell motility
@en
P2093
Lars Kjøller
P2860
P356
10.1515/BC.2002.002
P407
P577
2002-01-01T00:00:00Z