Induction of marked apoptosis in mammalian cancer cell lines by antisense DNA treatment to abolish expression of DENN (differentially expressed in normal and neoplastic cells)
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Down-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neuronsIG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugsIG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4/DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISCAkt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cellsGenes transactivated by hepatitis C virus core protein, a microarray assaymiR-181 interacts with signaling adaptor molecule DENN/MADD and enhances TNF-induced cell deathDENN/MADD/IG20 alternative splicing changes and cell death in Alzheimer's disease.MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment.MADD/DENN splice variant of the IG20 gene is a negative regulator of caspase-8 activation. Knockdown enhances TRAIL-induced apoptosis of cancer cells.
P2860
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P2860
Induction of marked apoptosis in mammalian cancer cell lines by antisense DNA treatment to abolish expression of DENN (differentially expressed in normal and neoplastic cells)
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2002 nî lūn-bûn
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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Induction of marked apoptosis ...... n normal and neoplastic cells)
@ast
Induction of marked apoptosis ...... n normal and neoplastic cells)
@en
Induction of marked apoptosis ...... n normal and neoplastic cells)
@nl
type
label
Induction of marked apoptosis ...... n normal and neoplastic cells)
@ast
Induction of marked apoptosis ...... n normal and neoplastic cells)
@en
Induction of marked apoptosis ...... n normal and neoplastic cells)
@nl
prefLabel
Induction of marked apoptosis ...... n normal and neoplastic cells)
@ast
Induction of marked apoptosis ...... n normal and neoplastic cells)
@en
Induction of marked apoptosis ...... n normal and neoplastic cells)
@nl
P2860
P356
P1476
Induction of marked apoptosis ...... n normal and neoplastic cells)
@en
P2093
Vincent T K Chow
P2860
P304
P356
10.1002/MC.10082
P407
P577
2002-11-01T00:00:00Z