No PUMA, no death: implications for p53-dependent apoptosis
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The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activitySKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicingPUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cellsSp1 and p73 activate PUMA following serum starvationp53 independent induction of PUMA mediates intestinal apoptosis in response to ischaemia-reperfusionDNA repair and aging: the impact of the p53 familyResistance and gain-of-resistance phenotypes in cancers harboring wild-type p53Puma joins the battery of BH3-only proteins that promote death and infarction during myocardial ischemiaSMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial eventsMultiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signalingBlocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis.PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis.PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cellsThe p53 network: cellular and systemic DNA damage responses in aging and cancer.AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.New insights into p53 activationMorpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development.SN50 enhances the effects of LY294002 on cell death induction in gastric cancer cell line SGC7901.Recent advances in p53 research and cancer treatmentCentrosomal protein 55 (Cep55) stability is negatively regulated by p53 protein through Polo-like kinase 1 (Plk1)Genetic variants of a BH3-only pro-apoptotic gene, PUMA, and risk of HPV16-associated squamous cell carcinoma of the head and neckPUMA mediates the combinational therapy of 5-FU and NVP-BEZ235 in colon cancerAS-IV protects against kidney IRI through inhibition of NF-κB activity and PUMA upregulationSynergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells.Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species.A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.Tumor suppressor protein p53 regulates megakaryocytic polyploidization and apoptosisAnti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway.Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicityOverexpression of OATP1B3 confers apoptotic resistance in colon cancer.DNA damage-induced cell death: lessons from the central nervous system.PUMA promotes Bax translocation by both directly interacting with Bax and by competitive binding to Bcl-X L during UV-induced apoptosis.Computational analysis of dynamical responses to the intrinsic pathway of programmed cell death.Hsp90 inhibitors promote p53-dependent apoptosis through PUMA and Bax.EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis.Pazopanib, a novel multi-kinase inhibitor, shows potent antitumor activity in colon cancer through PUMA-mediated apoptosis.What's new in p53?The relevance of protein-protein interactions for p53 function: the CPE contribution.Exploiting tyrosinase expression and activity in melanocytic tumors: quercetin and the central role of p53.
P2860
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P2860
No PUMA, no death: implications for p53-dependent apoptosis
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
No PUMA, no death: implications for p53-dependent apoptosis
@ast
No PUMA, no death: implications for p53-dependent apoptosis
@en
No PUMA, no death: implications for p53-dependent apoptosis
@nl
type
label
No PUMA, no death: implications for p53-dependent apoptosis
@ast
No PUMA, no death: implications for p53-dependent apoptosis
@en
No PUMA, no death: implications for p53-dependent apoptosis
@nl
altLabel
No PUMA, no death
@ast
No PUMA, no death
@en
prefLabel
No PUMA, no death: implications for p53-dependent apoptosis
@ast
No PUMA, no death: implications for p53-dependent apoptosis
@en
No PUMA, no death: implications for p53-dependent apoptosis
@nl
P3181
P1433
P1476
No PUMA, no death
@en
No PUMA, no death: implications for p53-dependent apoptosis
@en
P2093
P3181
P356
10.1016/S1535-6108(03)00249-6
P407
P577
2003-10-01T00:00:00Z