Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
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Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumorsLIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cellsGolgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogenMMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical propertiesMT1-MMP hemopexin domain exchange with MT4-MMP blocks enzyme maturation and trafficking to the plasma membrane in MCF7 cellsThe Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain: CRYSTAL STRUCTURE AND BIOLOGICAL FUNCTIONSMT1-MMP recognition by ERM proteins and its implication in CD44 sheddingUtilization of a novel recombinant myoglobin fusion protein expression system to characterize the tissue inhibitor of metalloproteinase (TIMP)-4 and TIMP-2 C-terminal domain and tails by mutagenesis. The importance of acidic residues in binding theChlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): the next decadeDegenerate wave and capacitive coupling increase human MSC invasion and proliferation while reducing cytotoxicity in an in vitro wound healing modelMT1-MMP proinvasive activity is regulated by a novel Rab8-dependent exocytic pathway.Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imagingLess is more: low expression of MT1-MMP is optimal to promote migration and tumourigenesis of breast cancer cells.A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1.Proteomic analysis of nipple aspirate fluid from women with early-stage breast cancer using isotope-coded affinity tags and tandem mass spectrometry reveals differential expression of vitamin D binding protein.Cloning and developmental characterization of Xenopus laevis membrane type-3 matrix metalloproteinase (MT3-MMP).The Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.Progress in matrix metalloproteinase research.Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition.Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits.Temporal gene expression profiling during rat femoral marrow ablation-induced intramembranous bone regenerationMMP-2 and MMP-14 Silencing Inhibits VEGFR2 Cleavage and Induces the Differentiation of Porcine Adipose-Derived Mesenchymal Stem Cells to Endothelial Cells.The Role of Interleukin-18, Oxidative Stress and Metabolic Syndrome in Alzheimer's Disease.Epidermal growth factor receptor-mediated membrane type 1 matrix metalloproteinase endocytosis regulates the transition between invasive versus expansive growth of ovarian carcinoma cells in three-dimensional collagenThe tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversityMatrix metalloproteases in head and neck cancer.The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif.Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cellsDiffusion of MMPs on the surface of collagen fibrils: the mobile cell surface-collagen substratum interface.Novel MT1-MMP small-molecule inhibitors based on insights into hemopexin domain function in tumor growthClusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils.Subepithelial corneal fibrosis partially due to epithelial-mesenchymal transition of ocular surface epitheliumLocalizing matrix metalloproteinase activities in the pericellular environment.TIMP independence of matrix metalloproteinase (MMP)-2 activation by membrane type 2 (MT2)-MMP is determined by contributions of both the MT2-MMP catalytic and hemopexin C domains.The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeuticsCritical role of transient activity of MT1-MMP for ECM degradation in invadopodiaLumican - derived peptides inhibit melanoma cell growth and migration.
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P2860
Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Homophilic complex formation o ...... d promotes tumor cell invasion
@nl
Homophilic complex formation o ...... promotes tumor cell invasion.
@ast
Homophilic complex formation o ...... promotes tumor cell invasion.
@en
type
label
Homophilic complex formation o ...... d promotes tumor cell invasion
@nl
Homophilic complex formation o ...... promotes tumor cell invasion.
@ast
Homophilic complex formation o ...... promotes tumor cell invasion.
@en
prefLabel
Homophilic complex formation o ...... d promotes tumor cell invasion
@nl
Homophilic complex formation o ...... promotes tumor cell invasion.
@ast
Homophilic complex formation o ...... promotes tumor cell invasion.
@en
P2093
P2860
P3181
P356
P1433
P1476
Homophilic complex formation o ...... d promotes tumor cell invasion
@en
P2093
Takamura A
P2860
P304
P3181
P356
10.1093/EMBOJ/20.17.4782
P407
P577
2001-09-01T00:00:00Z