Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12
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Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motilityInitiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene familyConservation of peptide acceptor preferences between Drosophila and mammalian polypeptide-GalNAc transferase ortholog pairs.Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster.Characterization of a UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase with an unusual lectin domain from the platyhelminth parasite Echinococcus granulosusIdentification of common and unique peptide substrate preferences for the UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substrates.N-Acetylgalactosaminyltransferase-14 as a potential biomarker for breast cancer by immunohistochemistry.Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22.Polypeptide GalNAc-transferases, ST6GalNAc-transferase I, and ST3Gal-transferase I expression in gastric carcinoma cell lines.Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysisEmerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases.A multistage genetic association study identifies breast cancer risk loci at 10q25 and 16q24Recent insights into the biological roles of mucin-type O-glycosylationInactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers.Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-12 in gastric and colonic cancer cell lines and in human colorectal cancer.Expression of UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-6 in gastric mucosa, intestinal metaplasia, and gastric carcinoma.Mucin core O-glycosylation is modulated by neighboring residue glycosylation status. Kinetic modeling of the site-specific glycosylation of the apo-porcine submaxillary mucin tandem repeat by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferasesDefective GALNT12 causes colorectal cancer 1 (CRCS1)Inherited deleterious variants in GALNT12 are associated with CRC susceptibility.Human male infertility and its genetic causes.Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography.Function of conserved aromatic residues in the Gal/GalNAc-glycosyltransferase motif of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.Role of GALNT12 in the genetic predisposition to attenuated adenomatous polyposis syndrome.Glycosylation-related gene expression in HT29-MTX-E12 cells upon infection by Helicobacter pylori.Altered glycosyltransferases in colorectal cancer.GALNT12 is not a major contributor of familial colorectal cancer type X.Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T15
P2860
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P2860
Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12
description
2002 nî lūn-bûn
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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@ast
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@en
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@nl
type
label
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@ast
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@en
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@nl
prefLabel
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@ast
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@en
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@nl
P2093
P2860
P1433
P1476
Molecular cloning and characte ...... nsferase family, pp-GalNAc-T12
@en
P2093
Hiroko Iwasaki
Jian-Ming Guo
Kouichi Tachibana
Lamei Cheng
P2860
P304
P356
10.1016/S0014-5793(02)03007-7
P407
P577
2002-07-01T00:00:00Z