Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics
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KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertilityLinking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severingCellular localization, oligomerization, and membrane association of the hereditary spastic paraplegia 3A (SPG3A) protein atlastinLoss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegiaRecognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severingMutations in the ER-shaping protein reticulon 2 cause the axon-degenerative disorder hereditary spastic paraplegia type 12Hereditary spastic paraplegia proteins REEP1, spastin, and atlastin-1 coordinate microtubule interactions with the tubular ER networkSpastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretionThe Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cellsStructure and ESCRT-III protein interactions of the MIT domain of human VPS4A.Regulation of microtubule severing by katanin subunits during neuronal development.A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10)Troyer syndrome protein spartin is mono-ubiquitinated and functions in EGF receptor traffickingDrosophila spastin regulates synaptic microtubule networks and is required for normal motor functionMig12, a novel Opitz syndrome gene product partner, is expressed in the embryonic ventral midline and co-operates with Mid1 to bundle and stabilize microtubulesThe Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic ParaplegiasA Common Substrate Recognition Mode Conserved between Katanin p60 and VPS4 Governs Microtubule Severing and Membrane Skeleton ReorganizationHereditary spastic paraplegia SPG4: what is known and not known about the disease.The nucleotide cycle of spastin correlates with its microtubule-binding propertiesMutation analysis of the spastin gene (SPG4) in patients in Germany with autosomal dominant hereditary spastic paraplegiaGene organization, evolution and expression of the microtubule-associated protein ASAP (MAP9)Effect of Ca2+ on the microtubule-severing enzyme p60-katanin. Insight into the substrate-dependent activation mechanismFunctional conservation of human Spastin in a Drosophila model of autosomal dominant-hereditary spastic paraplegiaGenetic and chemical modulation of spastin-dependent axon outgrowth in zebrafish embryos indicates a role for impaired microtubule dynamics in hereditary spastic paraplegia.Microtubule-targeting drugs rescue axonal swellings in cortical neurons from spastin knockout mice.Spastin and atlastin, two proteins mutated in autosomal-dominant hereditary spastic paraplegia, are binding partnersA cryptic promoter in the first exon of the SPG4 gene directs the synthesis of the 60-kDa spastin isoform.Role of spastin in apical domain control along the rhabdomere elongation in Drosophila photoreceptor.Motor neuron synapse and axon defects in a C. elegans alpha-tubulin mutant.DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics.Mutational spectrum of the SPG4 (SPAST) and SPG3A (ATL1) genes in Spanish patients with hereditary spastic paraplegia.The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes.Congenital bovine spinal dysmyelination is caused by a missense mutation in the SPAST gene.Cold temperature improves mobility and survival in Drosophila models of autosomal-dominant hereditary spastic paraplegia (AD-HSP).Valosin-containing protein-interacting membrane protein (VIMP) links the endoplasmic reticulum with microtubules in concert with cytoskeleton-linking membrane protein (CLIMP)-63Oligomerization of ZFYVE27 (Protrudin) is necessary to promote neurite extension.Alternative splicing of Spg7, a gene involved in hereditary spastic paraplegia, encodes a variant of paraplegin targeted to the endoplasmic reticulum.Role of spastin and protrudin in neurite outgrowth.Distinct novel mutations affecting the same base in the NIPA1 gene cause autosomal dominant hereditary spastic paraplegia in two Chinese families.Connecting the cytoskeleton to the endoplasmic reticulum and Golgi.
P2860
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P2860
Spastin, the protein mutated in autosomal dominant hereditary spastic paraplegia, is involved in microtubule dynamics
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Spastin, the protein mutated i ...... volved in microtubule dynamics
@ast
Spastin, the protein mutated i ...... volved in microtubule dynamics
@en
Spastin, the protein mutated i ...... volved in microtubule dynamics
@nl
type
label
Spastin, the protein mutated i ...... volved in microtubule dynamics
@ast
Spastin, the protein mutated i ...... volved in microtubule dynamics
@en
Spastin, the protein mutated i ...... volved in microtubule dynamics
@nl
prefLabel
Spastin, the protein mutated i ...... volved in microtubule dynamics
@ast
Spastin, the protein mutated i ...... volved in microtubule dynamics
@en
Spastin, the protein mutated i ...... volved in microtubule dynamics
@nl
P3181
P356
P1476
Spastin, the protein mutated i ...... volved in microtubule dynamics
@en
P2093
Alessia Errico
P304
P3181
P356
10.1093/HMG/11.2.153
P407
P577
2002-01-15T00:00:00Z