Evidence for sequential barriers and obligatory intermediates in apparent two-state protein folding
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Capture of monomeric refolding intermediate of human muscle creatine kinaseStructural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat proteinThe Plastic Energy Landscape of Protein Folding: A TRIANGULAR FOLDING MECHANISM WITH AN EQUILIBRIUM INTERMEDIATE FOR A SMALL PROTEIN DOMAINIs an intermediate state populated on the folding pathway of ubiquitin?Discrete kinetic models from funneled energy landscape simulationsA simple model predicts experimental folding rates and a hub-like topologyThe structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicityMultiple folding pathways of the SH3 domain.On the polymer physics origins of protein folding thermodynamics.Molecular dynamics simulations of the native and partially folded states of ubiquitin: influence of methanol cosolvent, pH, and temperature on the protein structure and dynamics.Rational design of protein stability: effect of (2S,4R)-4-fluoroproline on the stability and folding pathway of ubiquitinFolding of a LysM domain: entropy-enthalpy compensation in the transition state of an ideal two-state folder.Topology is the principal determinant in the folding of a complex all-alpha Greek key death domain from human FADDExperimental evidence for a frustrated energy landscape in a three-helix-bundle protein familyT-jump infrared study of the folding mechanism of coiled-coil GCN4-p1.Probing the folding intermediate of Rd-apocyt b562 by protein engineering and infrared T-jumpDemonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulationFull distance-resolved folding energy landscape of one single protein molecule.An unlocking/relocking barrier in conformational fluctuations of villin headpiece subdomainSystematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutantsDissecting the mechanical unfolding of ubiquitin.The experimental folding landscape of monomeric lactose repressor, a large two-domain protein, involves two kinetic intermediates.Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7.Phi-value analysis and the nature of protein-folding transition statesScattered Hammond plots reveal second level of site-specific information in protein folding: phi' (beta++).The denatured state dictates the topology of two proteins with almost identical sequence but different native structure and function.The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding proteinFree-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in acetylcholine-receptor channelsComplex energy landscape of a giant repeat protein.Frustration in biomoleculesThe folding pathway of a single domain in a multidomain protein is not affected by its neighbouring domain.Probing the folding intermediate of Bacillus subtilis RNase P protein by nuclear magnetic resonance.Hydrogen-exchange stability analysis of Bergerac-Src homology 3 variants allows the characterization of a folding intermediate in equilibriumApparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domainsMicrosecond unfolding kinetics of sheep prion protein reveals an intermediate that correlates with susceptibility to classical scrapie.GB1 is not a two-state folder: identification and characterization of an on-pathway intermediateA PDZ domain recapitulates a unifying mechanism for protein foldingHighly polarized C-terminal transition state of the leucine-rich repeat domain of PP32 is governed by local stability.Rational redesign of the folding pathway of a modular proteinEnhancing the stability and folding rate of a repeat protein through the addition of consensus repeats
P2860
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P2860
Evidence for sequential barriers and obligatory intermediates in apparent two-state protein folding
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Evidence for sequential barrie ...... rent two-state protein folding
@ast
Evidence for sequential barrie ...... rent two-state protein folding
@en
Evidence for sequential barrie ...... rent two-state protein folding
@nl
type
label
Evidence for sequential barrie ...... rent two-state protein folding
@ast
Evidence for sequential barrie ...... rent two-state protein folding
@en
Evidence for sequential barrie ...... rent two-state protein folding
@nl
prefLabel
Evidence for sequential barrie ...... rent two-state protein folding
@ast
Evidence for sequential barrie ...... rent two-state protein folding
@en
Evidence for sequential barrie ...... rent two-state protein folding
@nl
P1476
Evidence for sequential barrie ...... rent two-state protein folding
@en
P2093
Ignacio E Sánchez
P304
P356
10.1016/S0022-2836(02)01230-5
P407
P577
2003-01-10T00:00:00Z