Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs - Wikidata - wikimedia - TriplyDB

Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs

Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs

http://www.wikidata.org/entity/Q28218678

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Targeting G protein coupled receptor-related pathways as emerging molecular therapies Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism Identification of anti-malarial compounds as novel antagonists to chemokine receptor CXCR4 in pancreatic cancer cells Effects of the D1 Dopamine Receptor Agonist Dihydrexidine (DAR-0100A) on Working Memory in Schizotypal Personality Disorder Phenylpiperazine derivatives with selectivity for dopamine D3 receptors modulate cocaine self-administration in rats Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.Identification of G protein-biased agonists that fail to recruit β-arrestin or promote internalization of the D1 dopamine receptor.Third generation antipsychotic drugs: partial agonism or receptor functional selectivity?CODA-RET reveals functional selectivity as a result of GPCR heteromerization.Receptor conformations involved in dopamine D(2L) receptor functional selectivity induced by selected transmembrane-5 serine mutations.Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D₂ receptor agonists.Therapeutic potential of β-arrestin- and G protein-biased agonists.GPCR functional selectivity has therapeutic impact.Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia.D1/D2-dopamine receptor agonist dihydrexidine stimulates inspiratory motor output and depresses medullary expiratory neurons.Irving Page Lecture: 5-HT(2A) serotonin receptor biology: interacting proteins, kinases and paradoxical regulation.Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors.Dopamine receptor signaling and current and future antipsychotic drugs.Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective.Novel Dopamine Therapeutics for Cognitive Deficits in Schizophrenia.New Concepts in Dopamine D2 Receptor Biased Signaling and Implications for Schizophrenia Therapy.Identification and characterization of a novel class of atypical dopamine receptor agonists.Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling.Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways.The Gq and G12 families of heterotrimeric G proteins report functional selectivity.Ligand functional selectivity advances our understanding of drug mechanisms and drug discovery.Selective mode of action of guanidine-containing non-peptides at human NPFF receptors.Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists.A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses.

P2860

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P2860

Functional selectivity of dopamine receptor agonists. II. Actions of dihydrexidine in D2L receptor-transfected MN9D cells and pituitary lactotrophs

http://www.wikidata.org/entity/Q28218678

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2002年の論文

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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JPET.301.3.1179

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Journal of Pharmacology and Experimental Therapeutics

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Functional selectivity of dopa ...... ells and pituitary lactotrophs

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Bonita L Blake

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Cindy P Lawler

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Richard Mailman

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2002-06-01T00:00:00Z

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12023553

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