Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators
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Fuzziness: linking regulation to protein dynamicsClassification of intrinsically disordered regions and proteinsIntrinsically disordered proteins in a physics-based worldMapping the interactions of the p53 transactivation domain with the KIX domain of CBPRegulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivityFuzzy complexes: Specific binding without complete foldingStructure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC PromoterBinding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and ExperimentCooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domainGenetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repressionTyrosine phosphorylation within the intrinsically disordered cytosolic domains of the B-cell receptor: an NMR-based structural analysisThe importance of intrinsic disorder for protein phosphorylationAnticooperativity in a Glu-Lys-Glu salt bridge triplet in an isolated alpha-helical peptide.Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.The intrinsic disorder alphabet. III. Dual personality of serine.Modeling disordered protein interactions from biophysical principlesRegulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions.Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain.Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.Discrete molecular dynamics can predict helical prestructured motifs in disordered proteinsOverexpression of post-translationally modified peptides in Escherichia coli by co-expression with modifying enzymes.Binding-induced folding of a natively unstructured transcription factor.Molecular dynamics simulation of phosphorylated KID post-translational modification.Site-specific phosphorylation induces functionally active conformation in the intrinsically disordered N-terminal activation function (AF1) domain of the glucocorticoid receptor.Acquisition of a leucine zipper motif as a mechanism of antimorphy for an allele of the Drosophila Hox gene Sex combs reducedPhosphorylation induces sequence-specific conformational switches in the RNA polymerase II C-terminal domain.Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition.Expanding the proteome: disordered and alternatively folded proteins.Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.Experimental validation of the role of trifluoroethanol as a nanocrowder.Molecular recognition by the KIX domain and its role in gene regulation.Dual role of protein phosphorylation in DNA activator/coactivator binding.Secondary structure, a missing component of sequence-based minimotif definitions.HTLV-1 HBZ protein deregulates interactions between cellular factors and the KIX domain of p300/CBP.Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and foldingThe human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2Allosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300
P2860
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P2860
Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators
description
2002 nî lūn-bûn
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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@ast
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@en
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@nl
type
label
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@ast
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@en
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@nl
prefLabel
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@ast
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@en
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@nl
P2860
P50
P3181
P356
P1476
Roles of phosphorylation and h ...... nd inducible (CREB) activators
@en
P2093
Marc R Montminy
P2860
P304
42241-42248
P3181
P356
10.1074/JBC.M207361200
P407
P577
2002-08-23T00:00:00Z