The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
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Antioxidant c-FLIP inhibits Fas ligand-induced NF-kB activation in a phosphatidylinositol 3-kinase/Akt-dependent mannerEctopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosisCaspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiationInvolvement of caspase 8 and c-FLIPL in the proangiogenic effects of the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)Caspases: pharmacological manipulation of cell deathRipped to deathElevated NF-kappaB responses and FLIP levels in leukemic but not normal lymphocytes: reduction by salicylate allows TNF-induced apoptosisOnto better TRAILs for cancer treatmentFLIP the Switch: Regulation of Apoptosis and Necroptosis by cFLIPChondrocyte Apoptosis in the Pathogenesis of OsteoarthritisUbiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of HomeostasisS-Nitrosylation in TNF superfamily signaling pathway: Implication in cancerMolecular targets of TRAIL-sensitizing agents in colorectal cancerInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationRegulation of CD95/Fas signaling at the DISCPhotoreceptor cell death and rescue in retinal detachment and degenerationsMarine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathwaysRIPK-dependent necrosis and its regulation by caspases: a mystery in five actsGetting TRAIL back on track for cancer therapyc-FLIP-Short reduces type I interferon production and increases viremia with coxsackievirus B3Mechanism of procaspase-8 activation by c-FLIPLMolecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomainFLIP and the death effector domain familyAllogeneic transplantation, Fas signaling, and dysregulation of hepcidinThe role of sex differences in autophagy in the heart during coxsackievirus B3-induced myocarditisRaf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signalingChanges in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restrictionN-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathwaySpatial differences in active caspase-8 defines its role in T-cell activation versus cell deathCellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitmentConstitutive expression of murine c-FLIPR causes autoimmunity in aged miceA caspase-like decoy molecule enhances the activity of a paralogous caspase in the yellow fever mosquito, Aedes aegypti.Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.c-Fos as a proapoptotic agent in TRAIL-induced apoptosis in prostate cancer cellsHepatocyte death: a clear and present danger.The many roles of FAS receptor signaling in the immune systemThe caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signalingActivation of caspases-8 and -10 by FLIP(L).
P2860
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P2860
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The long form of FLIP is an ac ...... ath-inducing signaling complex
@ast
The long form of FLIP is an ac ...... ath-inducing signaling complex
@en
The long form of FLIP is an ac ...... ath-inducing signaling complex
@nl
type
label
The long form of FLIP is an ac ...... ath-inducing signaling complex
@ast
The long form of FLIP is an ac ...... ath-inducing signaling complex
@en
The long form of FLIP is an ac ...... ath-inducing signaling complex
@nl
prefLabel
The long form of FLIP is an ac ...... ath-inducing signaling complex
@ast
The long form of FLIP is an ac ...... ath-inducing signaling complex
@en
The long form of FLIP is an ac ...... ath-inducing signaling complex
@nl
P2093
P3181
P356
P1476
The long form of FLIP is an ac ...... ath-inducing signaling complex
@en
P2093
Christophe Briand
Donald W Nicholson
Margot Thome
Markus G Grütter
Nils Holler
Olivier Micheau
Pascal Schneider
P304
P3181
P356
10.1074/JBC.M206882200
P407
P50
P577
2002-11-22T00:00:00Z