Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells - Wikidata - wikimedia - TriplyDB

Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells

Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells

http://www.wikidata.org/entity/Q28235640

about

G Protein-Coupled Receptor Signaling in Stem Cells and Cancer Challenges in the clinical utility of the serum test for HER2 ECD Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease Involvement of TACE/ADAM17 and ADAM10 in etoposide-induced apoptosis of germ cells in rat spermatogenesis HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?A functional role for ADAM10 in human immunodeficiency virus type-1 replication Interference-Free HER2 ECD as a Serum Biomarker in Breast Cancer.Functional protease profiling for diagnosis of malignant disease.ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer.Targeted treatment of advanced and metastaticbreast cancer with lapatinib.Targeting the function of the HER2 oncogene in human cancer therapeutics.The tyrosine kinase receptor ROR1 is constitutively phosphorylated in chronic lymphocytic leukemia (CLL) cells.Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma Monitoring serum HER2 levels in breast cancer patients.Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells Relationships between serum HER2 ECD, TIMP-1 and clinical outcomes in Taiwanese breast cancer SheddomeDB: the ectodomain shedding database for membrane-bound shed markers.Antibodies binding the ADAM10 substrate recognition domain inhibit Eph function Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.Leukocyte cell surface proteinases: regulation of expression, functions, and mechanisms of surface localization.TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective.Truncated p110 ERBB2 induces mammary epithelial cell migration, invasion and orthotopic xenograft formation, and is associated with loss of phosphorylated STAT5 Molecular analysis of neural crest migration EGFR/HER2 in breast cancer: a biological approach for molecular diagnosis and therapy.A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis.Allosteric MEK1/2 inhibitor refametinib (BAY 86-9766) in combination with sorafenib exhibits antitumor activity in preclinical murine and rat models of hepatocellular carcinoma.Role of trastuzumab in the management of HER2-positive metastatic breast cancer.Potential of ErbB4 antibodies for cancer therapy.Herceptin resistance database for understanding mechanism of resistance in breast cancer patients.Bringing cancer serological diagnosis to a new level: focusing on HER2, protein ectodomain shedding and neoepitope technology.Evaluation of HER2 in breast cancer: reality and expectations.The Mysterious Ways of ErbB2/HER2 Trafficking The human β-amyloid precursor protein: biomolecular and epigenetic aspects.MEK 1/2 inhibitors in the treatment of hepatocellular carcinoma.When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase.Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function.Perspectives of HER2-targeting in gastric and esophageal cancer.Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm.Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array.

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P2860

Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells

http://www.wikidata.org/entity/Q28235640

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2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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Brian Metcalf

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Chunhong He

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Cindy Marando

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Colin Zhang

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Costas Agrios

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David Burns

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Dawn Ellis

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Ding-Quan Qian

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Eric Shi

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Gengjie Yang

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