Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein
about
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learningDiscs large (Dlg1) complexes in lymphocyte activationDGKι regulates presynaptic release during mGluR-dependent LTDBinding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor proteinTwo independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domainMulti-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteinsExocyst complex subunit sec8 binds to postsynaptic density protein-95 (PSD-95): a novel interaction regulated by cypin (cytosolic PSD-95 interactor)Recruitment of an alternatively spliced form of synaptojanin 2 to mitochondria by the interaction with the PDZ domain of a mitochondrial outer membrane protein.Link of the unique oncogenic properties of adenovirus type 9 E4-ORF1 to a select interaction with the candidate tumor suppressor protein ZO-2A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epitheliaCraniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large genep38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAPIntramolecular interactions regulate SAP97 binding to GKAPInteractions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteinsThe role of SAP97 in synaptic glutamate receptor dynamicsSynaptic SAP97 isoforms regulate AMPA receptor dynamics and access to presynaptic glutamateNck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathwaysThe nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activityGKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering moleculesDirect interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapsesDlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cellsThe junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brainOncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressorSubunit- and pathway-specific localization of NMDA receptors and scaffolding proteins at ganglion cell synapses in rat retinaBassoon, a novel zinc-finger CAG/glutamine-repeat protein selectively localized at the active zone of presynaptic nerve terminalsInteractions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2SAP97 controls the trafficking and resensitization of the beta-1-adrenergic receptor through its PDZ2 and I3 domainsCa2+/calmodulin-dependent protein kinase II binds to and phosphorylates a specific SAP97 splice variant to disrupt association with AKAP79/150 and modulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate receptor (AMPAR) actiOrganizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large.Modular organization of the PDZ domains in the human discs-large protein suggests a mechanism for coupling PDZ domain-binding proteins to ATP and the membrane cytoskeleton.Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epitheliaFast and accurate resonance assignment of small-to-large proteins by combining automated and manual approaches.Postmortem brain: an underutilized substrate for studying severe mental illnessSeveral E4 region functions influence mammary tumorigenesis by human adenovirus type 9Mass of the postsynaptic density and enumeration of three key moleculesDLG-1 is a MAGUK similar to SAP97 and is required for adherens junction formation.Requirement for Dlgh-1 in planar cell polarity and skeletogenesis during vertebrate development.ER to synapse trafficking of NMDA receptorsAcute BDNF treatment upregulates GluR1-SAP97 and GluR2-GRIP1 interactions: implications for sustained AMPA receptor expression.Proteins interactions implicated in AMPA receptor trafficking: a clear destination and an improving route map.
P2860
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P2860
Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Molecular characterization and ...... large tumor suppressor protein
@ast
Molecular characterization and ...... large tumor suppressor protein
@en
Molecular characterization and ...... large tumor suppressor protein
@nl
type
label
Molecular characterization and ...... large tumor suppressor protein
@ast
Molecular characterization and ...... large tumor suppressor protein
@en
Molecular characterization and ...... large tumor suppressor protein
@nl
prefLabel
Molecular characterization and ...... large tumor suppressor protein
@ast
Molecular characterization and ...... large tumor suppressor protein
@en
Molecular characterization and ...... large tumor suppressor protein
@nl
P2093
P1476
Molecular characterization and ...... large tumor suppressor protein
@en
P2093
B M Müller
C C Garner
C Cases-Langhoff
E D Gundelfinger
P304
P356
10.1523/JNEUROSCI.15-03-02354.1995
P407
P433
P577
1995-03-01T00:00:00Z