XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates - Wikidata - wikimedia - TriplyDB

XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates

XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates

http://www.wikidata.org/entity/Q28237523

about

Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates Radiation cataracts: mechanisms involved in their long delayed occurrence but then rapid progression.Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase.Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining.Partial loss of the DNA repair scaffolding protein, Xrcc1, results in increased brain damage and reduced recovery from ischemic stroke in mice.Neurological disorders associated with DNA strand-break processing enzymes.Recognition and repair of chemically heterogeneous structures at DNA ends Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.XRCC1 Arg194Trp polymorphism, risk of nonmelanoma skin cancer and extramammary Paget's disease in a Japanese population.XRCC1 and DNA polymerase beta in cellular protection against cytotoxic DNA single-strand breaks.Brain capacity for repair of oxidatively damaged DNA and preservation of neuronal function.The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase.Coordination of DNA single strand break repair.DNA end-processing enzyme polynucleotide kinase as a potential target in the treatment of cancer.The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair.Characterization of DNA Substrate Binding to the Phosphatase Domain of the DNA Repair Enzyme Polynucleotide Kinase/Phosphatase DNA 3'-phosphatase activity is critical for rapid global rates of single-strand break repair following oxidative stress.Independent mechanisms of stimulation of polynucleotide kinase/phosphatase by phosphorylated and non-phosphorylated XRCC1.Polymorphisms in the DNA repair gene XRCC1 and associations with systemic lupus erythematosus risk in the Taiwanese Han Chinese population.

P2860

Q27676221-A5088053-88AE-4BC2-AAEC-936DD6D1E3D7 Q33323351-F091083D-F92F-4E8E-8C15-AE69E89CD371 Q33593867-A6058349-0845-4F7E-BBA1-BBAC2B5E2873 Q33741181-2E5FF07F-4C8F-41DA-ADDE-EB164F62DF40 Q33875792-6DFA8E21-EF27-4491-B515-961B1B0129BD Q34333731-C6D0ED2C-38B1-484A-A789-A117F434CEA7 Q34476266-C814CBAF-AECA-4507-8C6F-D0AF5436D57A Q34535722-A4DD3FDB-E8E0-4C90-92E7-4E92B929C52A Q35002075-9AFD61DF-C6B6-4909-AF29-91A0D795F403 Q35099098-1D54C4D5-79BF-4D5D-A9FB-FD2D5D807894 Q36055901-032E9CE3-F3B0-4FF2-B7EF-2E3D4F39D04B Q36629377-4CF7CFEF-4A5D-4078-8F43-BFDBF2803A2B Q37122200-6BB2CE70-3E8A-49AF-8C33-4A26B856AF03 Q37138573-6F537509-4D77-4022-B965-25E2B1E921AE Q37393491-EDA181B1-9941-4943-A183-186010259DCB Q39021578-EE762CC9-19B3-4203-A3B3-ED9062C6F101 Q39866360-1CA61748-43B7-46E6-9FAD-DAEB210F8909 Q41890636-2ABF57B7-1A7A-458E-89E8-BCCDF85DB2B9 Q42091519-B4939851-325D-464F-975A-DF1AAB88A77F Q42255865-2A78FC5A-79BF-409F-8E70-4718A0319201 Q42931241-539BEF3A-D364-46E5-AF0A-5B0B169CA268 Q54456574-B6D2A066-39F5-46D6-B196-22AF99012EEF

P2860

XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates

http://www.wikidata.org/entity/Q28237523

description

2007 nî lūn-bûn

@nan

2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@ast

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@en

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@nl

type

label

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@ast

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@en

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@nl

prefLabel

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@ast

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@en

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@nl

P1433

Q28237523-98073501-1954-4B49-A7FD-1ADA4ECAE682

P1476

Q28237523-C25E7873-A3A4-4BE5-B1A5-9D22829E1376

P2093

Q28237523-268C9E68-EC78-481E-8328-D0A56C285FD2

Q28237523-385591BF-238A-47BC-B50A-51A9C7645C30

Q28237523-579DC2B9-0CCF-4A3E-8F49-1C218D9C544D

Q28237523-5C4FBBCE-787C-4127-BB5E-180CC49F3BAC

Q28237523-849412D1-52D8-4B4B-8132-21BEAA1104A4

Q28237523-90DBAACE-C6A2-4389-A4F1-9B68F7C2B45C

Q28237523-C2B5FB24-3A0F-4A0C-867F-AA76A29D454E

Q28237523-F0446A9B-08CD-4A25-81C7-F01A845591E1

P2860

Q28237523-01696B47-3E3E-4389-ADDF-D6479D232E6E

Q28237523-038038F4-B6D8-46A1-8F98-5E221C78B116

Q28237523-08E331A0-DA00-4F86-A706-A4A14B3B6A90

Q28237523-0A4014E6-84EB-46E0-9C39-2DBFAF13A147

Q28237523-11F07A7D-C719-4FA2-AE84-7CE403FAACC4

Q28237523-21D4172F-BE19-4834-8538-38DA3E3F0908

Q28237523-2C7588E0-FE16-4566-99DB-6A8C0BA51F71

Q28237523-2E620C8D-6576-4D97-AC0E-AC73C6D288EC

Q28237523-38E2420E-7E4D-43AF-A6DB-52BEA8FC1078

Q28237523-463FD6F8-F83A-4F62-B0F0-9B34F9BEFD79

P304

Q28237523-2E2BD362-F64C-40E5-9095-C69441D03B0A

P31

Q28237523-C68F610B-8899-47BB-B38C-21493D631A18

P356

Q28237523-A8470F8B-FEA2-4148-9912-D8144B18942F

P407

Q28237523-550AF17E-5E3B-4FF9-AADA-7CB9BC562689

P433

Q28237523-81C35AAA-1071-4BFF-88B5-F6BA4673EFAE

P478

Q28237523-5D0ADE30-7AC1-4EA5-9D50-9EFCBAF641CF

P577

Q28237523-0B5E0E94-6818-461A-AB07-F23716DF304F

P5875

Q28237523-16D421E5-2C94-45C3-9394-C9F0E572EC37

P698

Q28237523-821DF8BA-CA82-4EA6-BE6E-7DDE5DA04D21

P356

P1433

Journal of Biological Chemistry

P1476

XRCC1 stimulates polynucleotid ...... from DNA repair intermediates

@en

P2093

Carol E Cass

http://www.w3.org/2001/XMLSchema#string

César A Virgen

http://www.w3.org/2001/XMLSchema#string

Elizabeth Silver

http://www.w3.org/2001/XMLSchema#string

Feridoun Karimi-Busheri

http://www.w3.org/2001/XMLSchema#string

Keith W Caldecott

http://www.w3.org/2001/XMLSchema#string

Mesfin Fanta

http://www.w3.org/2001/XMLSchema#string

Michael Weinfeld

http://www.w3.org/2001/XMLSchema#string

Rajam S Mani

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3'-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage

Molecular characterization of a human DNA kinase

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV

XRCC1 co-localizes and physically interacts with PCNA

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Solution structure of the single-strand break repair protein XRCC1 N-terminal domain

P304

28004-13

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M704867200

http://www.w3.org/2001/XMLSchema#string

P407

P433

38

http://www.w3.org/2001/XMLSchema#string

P478

282

http://www.w3.org/2001/XMLSchema#string

P577

2007-09-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6187245

http://www.w3.org/2001/XMLSchema#string

P698

17650498

http://www.w3.org/2001/XMLSchema#string