Anti-obesity effects of small molecule melanin-concentrating hormone receptor 1 (MCHR1) antagonists
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Effects of the MCH1 receptor antagonist SNAP 94847 on high-fat food-reinforced operant responding and reinstatement of food seeking in ratsA systematic SNP selection approach to identify mechanisms underlying disease aetiology: linking height to post-menopausal breast and colorectal cancer riskHigh-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1.The pharmacological properties of a novel MCH1 receptor antagonist isolated from combinatorial libraries.New central targets for the treatment of obesity.Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1Evaluation of AMG 076, a potent and selective MCHR1 antagonist, in rodent and primate obesity modelsAnimals models of MCH function and what they can tell us about its role in energy balanceProfiling the interaction mechanism of quinoline/quinazoline derivatives as MCHR1 antagonists: an in silico method.Two naturally occurring mutations in the type 1 melanin-concentrating hormone receptor abolish agonist-induced signaling.Pharmacological treatment of obesity in children and adolescents: present and futureA role for Melanin-Concentrating Hormone in learning and memory.Peptides and their potential role in the treatment of diabetes and obesity.[¹⁸F]FE@SNAP-A new PET tracer for the melanin concentrating hormone receptor 1 (MCHR1): microfluidic and vessel-based approachesMelanin-concentrating hormone as a mediator of intestinal inflammation.Anti-melanin-concentrating hormone treatment attenuates chronic experimental colitis and fibrosis.Preparation and First Preclinical Evaluation of [(18)F]FE@SNAP: A Potential PET Tracer for the Melanin-Concentrating Hormone Receptor-1 (MCHR1)Can neuropeptides treat obesity? A review of neuropeptides and their potential role in the treatment of obesity.MCH receptors/gene structure-in vivo expression.Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists.Cellular models for the study of the pharmacology and signaling of melanin-concentrating hormone receptors.Recent progress in the discovery of melanin-concentrating hormone 1-receptor antagonists.Regulated Control of Melanin-Concentrating Hormone Receptor 1 through Posttranslational Modifications.The MCH(1) receptor, an anti-obesity target, is allosterically inhibited by 8-methylquinoline derivatives possessing subnanomolar binding and long residence times.Approved and Off-Label Uses of Obesity Medications, and Potential New Pharmacologic Treatment Options.Mechanism of the anti-obesity effects induced by a novel melanin-concentrating hormone 1-receptor antagonist in mice.Radiosynthesis of [11C]SNAP-7941--the first PET-tracer for the melanin concentrating hormone receptor 1 (MCHR1).Hypothalamus transcriptome profile suggests an anorexia-cachexia syndrome in the anx/anx mouse model.Pmch expression during early development is critical for normal energy homeostasis.
P2860
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P2860
Anti-obesity effects of small molecule melanin-concentrating hormone receptor 1 (MCHR1) antagonists
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@ast
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@en
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@nl
type
label
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@ast
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@en
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@nl
prefLabel
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@ast
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@en
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@nl
P1433
P1476
Anti-obesity effects of small ...... receptor 1 (MCHR1) antagonists
@en
P2093
David R Luthin
P304
P356
10.1016/J.LFS.2007.05.029
P407
P577
2007-07-19T00:00:00Z