Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma
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The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikisDuplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2Characterization of a family of novel cysteine- serine-rich nuclear proteins (CSRNP)A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targetsIntroduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell deathTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsInteraction of p58(PITSLRE), a G2/M-specific protein kinase, with cyclin D3Genomic structure and mutational analysis of the human KIF1B gene which is homozygously deleted in neuroblastoma at chromosome 1p36.2Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factorDelineation of mechanisms and regions of dosage imbalance in complex rearrangements of 1p36 leads to a putative gene for regulation of cranial suture closureIdentification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line.Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefitinib.Genome instability model of metastatic neuroblastoma tumorigenesis by a dictionary learning algorithm.Expression of the ALK tyrosine kinase gene in neuroblastoma.MYCL genotypes and loss of heterozygosity in non-small-cell lung cancerAllelic imbalance and instability of microsatellite loci on chromosome 1p in human non-small-cell lung cancer.Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor.Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival.Elimination of cyclin D1 in vertebrate cells leads to an altered cell cycle phenotype, which is rescued by overexpression of murine cyclins D1, D2, or D3 but not by a mutant cyclin D1.The MYCN oncogene is a direct target of miR-34a.The SDF-1 rs1801157 Polymorphism is Associated with Cancer Risk: An Update Pooled Analysis and FPRP Test of 17,876 Participants.The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy.PITSLRE protein kinase activity is associated with apoptosis.Regulation of stability of cyclin-dependent kinase CDK11p110 and a caspase-processed form, CDK11p46, by Hsp90.Analysis of mutations and identification of several polymorphisms in the putative promoter region of the P34CDC2-related CDC2L1 gene located at 1P36 in melanoma cell lines and melanoma families.Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers.DNA fragmentation factor 45 (DFF45) gene at 1p36.2 is homozygously deleted and encodes variant transcripts in neuroblastoma cell line.Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency.Genomic instability in 1p and human malignancies.Oncogenes and tumor suppressor genes in cutaneous malignant melanoma.Cell death induction by receptors of the TNF family: towards a molecular understanding.Cloning of cDNAs encoding Bombyx homologues of Cdc2 and Cdc2-related kinase from eggs.Analyses of CDC2L1 gene mutations in keloid tissue.Alterations of p73 preferentially occur in gastric adenocarcinomas with foveolar epithelial phenotype.Duplication of a Genomic Region Containing theCdc2L1-2andMMP21-22Genes on Human Chromosome 1p36.3 and their Linkage to D1Z2
P2860
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P2860
Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@ast
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@en
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@nl
type
label
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@ast
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@en
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@nl
prefLabel
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@ast
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@en
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@nl
P2093
P2860
P3181
P356
P1433
P1476
Alterations in the PITSLRE pro ...... p36 in childhood neuroblastoma
@en
P2093
G Richmond
M Valentine
P2860
P2888
P3181
P356
10.1038/NG0794-370
P407
P577
1994-07-01T00:00:00Z