Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver
about
Molecular phylogeny of the antiangiogenic and neurotrophic serpin, pigment epithelium derived factor in vertebratesHuman hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genesCREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expressionTwo initiator-like elements are required for the combined activation of the human apolipoprotein C-III promoter by upstream stimulatory factor and hepatic nuclear factor-4An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell typesNetwork insights into the genes regulated by hepatocyte nuclear factor 4 in response to drug induced perturbations: a reviewAssessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.Proof of concept: network and systems biology approaches aid in the discovery of potent anticancer drug combinations.Assessing self-renewal and differentiation in human embryonic stem cell lines.Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human isletsBest practice guidelines for the molecular genetic diagnosis of maturity-onset diabetes of the young.Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4.A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitusThe HNF4A R76W mutation causes atypical dominant Fanconi syndrome in addition to a β cell phenotype.Orphan nuclear receptors as targets for drug development.Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.The orphan nuclear receptors at their 25-year reunion.Orphan nuclear receptor HNF-4 binds to the human coagulation factor VII promoter.Critical structural elements and multitarget protein interactions of the transcriptional activator AF-1 of hepatocyte nuclear factor 4.Characterization of a dominant negative mutant form of the HNF-4 orphan receptor.Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4alpha1.Regulatory mechanisms controlling human hepatocyte nuclear factor 4alpha gene expression.The activity of the activation function 2 of the human hepatocyte nuclear factor 4 (HNF-4alpha) is differently modulated by F domains from various origins.Three isoforms of a hepatocyte nuclear factor-4 transcription factor with tissue- and stage-specific expression in the adult mosquito.Utilization of recombinant adenovirus and dominant negative mutants to characterize hepatocyte nuclear factor 4-regulated apolipoprotein AI and CIII expression.Activation of glucokinase gene expression by hepatic nuclear factor 4alpha in primary hepatocytes.Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha and 4 alpha in maturity-onset diabetes of the young and hyperinsulinemic hypoglycemia.Functional domains of the nuclear receptor hepatocyte nuclear factor 4.Clinical heterogeneity of hyperinsulinism due to HNF1A and HNF4A mutations.The Nuclear Receptor Field: A Historical Overview and Future ChallengesIdentification of target genes in cardiomyopathy with fibrosis and cardiac remodeling
P2860
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P2860
Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver
description
1994 nî lūn-bûn
@nan
1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@ast
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@en
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@nl
type
label
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@ast
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@en
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@nl
prefLabel
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@ast
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@en
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@nl
P2093
P1433
P1476
Cloning and sequencing of cDNA ...... of two isoforms in human liver
@en
P2093
P304
P356
10.1016/0378-1119(94)90079-5
P407
P577
1994-09-30T00:00:00Z