Membrane topology of the amiloride-sensitive epithelial sodium channel
about
Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunitsInteraction of the synaptic protein PICK1 (protein interacting with C kinase 1) with the non-voltage gated sodium channels BNC1 (brain Na+ channel 1) and ASIC (acid-sensing ion channel)A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channelBNaC1 and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channelsRegulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.Membrane topology and multimeric structure of a mechanosensitive channel protein of Escherichia coliIdentification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndromeWW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndromeAnalysis of the membrane topology of the acid-sensing ion channel 2aCell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approachA long isoform of the epithelial sodium channel alpha subunit forms a highly active channelEpithelial sodium channel (ENaC) family: Phylogeny, structure-function, tissue distribution, and associated inherited diseasesBinding of the proline-rich region of the epithelial Na+ channel to SH3 domains and its association with specific cellular proteins.Expression and purification of the alpha subunit of the epithelial sodium channel, ENaC.Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channelThe diagnosis of Liddle syndrome by identification of a mutation in the beta subunit of the epithelial sodium channel.The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones.Functional domains within the degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels.Activation of a latent nuclear localization signal in the NH2 terminus of γ-ENaC initiates feedback regulation of channel activity.Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.The heterotetrameric architecture of the epithelial sodium channel (ENaC).Point mutations in alpha bENaC regulate channel gating, ion selectivity, and sensitivity to amiloride.New role for plasmin in sodium homeostasis.The N-terminal domain allosterically regulates cleavage and activation of the epithelial sodium channel.AF17 facilitates Dot1a nuclear export and upregulates ENaC-mediated Na+ transport in renal collecting duct cells.Subunit stoichiometry of a core conduction element in a cloned epithelial amiloride-sensitive Na+ channel.Tetraethylammonium block of the BNC1 channel.A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second proteaseExpression cloning of the cDNA for a polypeptide associated with rat hepatic sinusoidal reduced glutathione transport: characteristics and comparison with the canalicular transporter.A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a.Second transmembrane domain modulates epithelial sodium channel gating in response to shear stressDisruption of the beta subunit of the epithelial Na+ channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype.ENaC structure and function in the wake of a resolved structure of a family member.TMPRSS4-dependent activation of the epithelial sodium channel requires cleavage of the γ-subunit distal to the furin cleavage siteExpression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiaeMolecular mechanisms of ubiquitin-dependent membrane trafficMultiple residues in the distal C terminus of the α-subunit have roles in modulating human epithelial sodium channel activity.Sequence and transmembrane topology of MEC-4, an ion channel subunit required for mechanotransduction in Caenorhabditis elegans.Ripped pocket and pickpocket, novel Drosophila DEG/ENaC subunits expressed in early development and in mechanosensory neurons.
P2860
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P2860
Membrane topology of the amiloride-sensitive epithelial sodium channel
description
1994 nî lūn-bûn
@nan
1994 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Membrane topology of the amiloride-sensitive epithelial sodium channel
@ast
Membrane topology of the amiloride-sensitive epithelial sodium channel
@en
Membrane topology of the amiloride-sensitive epithelial sodium channel
@nl
type
label
Membrane topology of the amiloride-sensitive epithelial sodium channel
@ast
Membrane topology of the amiloride-sensitive epithelial sodium channel
@en
Membrane topology of the amiloride-sensitive epithelial sodium channel
@nl
prefLabel
Membrane topology of the amiloride-sensitive epithelial sodium channel
@ast
Membrane topology of the amiloride-sensitive epithelial sodium channel
@en
Membrane topology of the amiloride-sensitive epithelial sodium channel
@nl
P2093
P3181
P1476
Membrane topology of the amiloride-sensitive epithelial sodium channel
@en
P2093
F J McDonald
J B Stokes
P M Snyder
P304
P3181
P407
P577
1994-09-30T00:00:00Z