mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass - Wikidata - wikimedia - TriplyDB

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

http://www.wikidata.org/entity/Q28239563

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Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease Regulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glance Caloric restriction and exercise "mimetics'': Ready for prime time?Differential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell Transplantation Sarcopenia: pharmacology of today and tomorrow Leveraging 3D chemical similarity, target and phenotypic data in the identification of drug-protein and drug-adverse effect associations Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise Ursolic acid increases glucose uptake through the PI3K signaling pathway in adipocytes Prioritizing therapeutics for lung cancer: an integrative meta-analysis of cancer gene signatures and chemogenomic data A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions Prediction of Candidate Drugs for Treating Pancreatic Cancer by Using a Combined Approach The Signature of MicroRNA Dysregulation in Muscle Paralyzed by Spinal Cord Injury Includes Downregulation of MicroRNAs that Target Myostatin Signaling A mixture of apple pomace and rosemary extract improves fructose consumption-induced insulin resistance in rats: modulation of sarcolemmal CD36 and glucose transporter-4 Transcriptional data: a new gateway to drug repositioning?Computational drug repositioning: from data to therapeutics.Mechanisms of protein balance in skeletal muscle.Systems-based discovery of tomatidine as a natural small molecule inhibitor of skeletal muscle atrophy.Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy.p53 and ATF4 mediate distinct and additive pathways to skeletal muscle atrophy during limb immobilization.Recent developments in the treatment of cachexia: highlights from the 6th Cachexia Conference.A genomic signature approach to rescue ΔF508-cystic fibrosis transmembrane conductance regulator biosynthesis and function.Ursolic Acid-induced elevation of serum irisin augments muscle strength during resistance training in men.Ursolic acid induces neural regeneration after sciatic nerve injury.Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy.Paracrine effects of IGF-1 overexpression on the functional decline due to skeletal muscle disuse: molecular and functional evaluation in hindlimb unloaded MLC/mIgf-1 transgenic mice Systematic evaluation of connectivity map for disease indications Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy.Network based elucidation of drug response: from modulators to targets.Methyl jasmonate-elicited transcriptional responses and pentacyclic triterpene biosynthesis in sweet basil.Muscle dysfunction in patients with lung diseases: a growing epidemic.External physical and biochemical stimulation to enhance skeletal muscle bioengineering Current nutritional recommendations and novel dietary strategies to manage sarcopenia Novel intriguing strategies attenuating to sarcopenia Evidence for metabolic aberrations in asymptomatic persons with type 2 diabetes after initiation of simvastatin therapy A gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mapping High motivation for exercise is associated with altered chromatin regulators of monoamine receptor gene expression in the striatum of selectively bred mice.Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database.Stress-induced skeletal muscle Gadd45a expression reprograms myonuclei and causes muscle atrophy.A review of connectivity map and computational approaches in pharmacogenomics.

P2860

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P2860

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass

http://www.wikidata.org/entity/Q28239563

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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mRNA expression signatures of ...... und that increases muscle mass

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J.CMET.2011.03.020

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Cell Metabolism

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mRNA expression signatures of ...... und that increases muscle mass

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P2093

Daniel K Fox

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Fariborz Alipour

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Kale S Bongers

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Scott M Ebert

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Sharon E Malmberg

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Steven D Kunkel

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P2860

A novel ubiquitin-binding protein ZNF216 functioning in muscle atrophy

Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Pharmacology of oleanolic acid and ursolic acid

Identification of ubiquitin ligases required for skeletal muscle atrophy

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake.

The transcription factor ATF4 promotes skeletal myofiber atrophy during fasting.

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311558

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10.1016/J.CMET.2011.03.020

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6

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Richard K Shields

Christopher M Adams

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2011-06-01T00:00:00Z

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51191834

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21641545

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3120768

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