Role of PTPN22 in type 1 diabetes and other autoimmune diseases
about
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in miceFoxp3 occupancy and regulation of key target genes during T-cell stimulationAutoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residueRobust associations of four new chromosome regions from genome-wide analyses of type 1 diabetesSmall molecule tools for functional interrogation of protein tyrosine phosphatasesGenetics of type 1 diabetesRisk factors and primary prevention trials for type 1 diabetesA Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune DiseasesImmunogenetics of type 1 diabetes mellitusIntegrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for IL-2 signaling genes in type 1 diabetes, and cytokine signaling genes in Crohn's diseaseFollow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.The autoimmunity risk variant LYP-W620 cooperates with CSK in the regulation of TCR signaling.Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.Worldwide population differentiation at disease-associated SNPs.Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia.ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis.Association of the protein tyrosine phosphatase non-receptor 22 polymorphism (PTPN22) with endometriosis: a meta-analysis.Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology.The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes.Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases.Target-specific control of lymphoid-specific protein tyrosine phosphatase (Lyp) activityPTPN22 1858C>T gene polymorphism in patients with SLE: association with serological and clinical resultsAltered B cell homeostasis and toll-like receptor 9-driven response in type 1 diabetes carriers of the C1858T PTPN22 allelic variant: implications in the disease pathogenesisDetection of T cell responses to a ubiquitous cellular protein in autoimmune diseaseEvaluation of neonatal streptozotocin induced diabetic rat model for the development of cataract.A co-association network analysis of the genetic determination of pig conformation, growth and fatness.Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosusVariation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia.Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomainLinkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.Prospective evaluation of glutamine and phospholipids levels in first degree relatives of patients with Type 1 Diabetes from a multiethnic populationBreakdown in peripheral tolerance in type 1 diabetes in mice and humansAssociation of the PTPN22 R620W polymorphism with increased risk for SLE in the genetically homogeneous population of Crete.Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK.K-RAS GTPase- and B-RAF kinase-mediated T-cell tolerance defects in rheumatoid arthritis.Prediction and prevention of type 1 diabetes: update on success of prediction and struggles at preventionHLA-DQB1* alleles and genetic susceptibility to type 1 diabetes mellitus.Metagenomics and personalized medicine.Cells of the synovium in rheumatoid arthritis. Dendritic cells.
P2860
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P2860
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@ast
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@en
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@nl
type
label
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@ast
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@en
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@nl
prefLabel
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@ast
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@en
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@nl
P3181
P1476
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
@en
P2093
Tomas Mustelin
Torkel Vang
P304
P3181
P356
10.1016/J.SMIM.2006.03.008
P407
P577
2006-08-01T00:00:00Z