about
Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancersMethylation-specific PCR: a novel PCR assay for methylation status of CpG islandsRegulation of p16CDKN2 expression and its implications for cell immortalization and senescenceMolecular genetic analysis of giant cell glioblastomasTargeting TGF-β signaling in cancerPharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts.TGFbeta in CancerHigh resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMinerExpression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescenceHigh-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances.Retinoblastoma loss modulates DNA damage response favoring tumor progressionDNA copy number losses in human neoplasms.Loss of heterozygosity at the Ink4a/Arf locus facilitates Abelson virus transformation of pre-B cellsIntegrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes.Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks.Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.Inhibition of cyclin-dependent kinases by p21p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.Cooperative effects of INK4a and ras in melanoma susceptibility in vivo.Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes.Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activationDetailed characterization of alterations of chromosomes 7, 9, and 10 in glioblastomas as assessed by single-nucleotide polymorphism arrays.Identification of p18 INK4c as a tumor suppressor gene in glioblastoma multiformeInhibitors of Glioma Growth that Reveal the Tumour to the Immune System.INK4a-ARF alterations in liver cell adenomaClinical stratification of glioblastoma based on alterations in retinoblastoma tumor suppressor protein (RB1) and association with the proneural subtypeFrequent p16INK4 (MTS1) gene inactivation in testicular germ cell tumors.Molecular genetic alterations in radiation-induced astrocytomas.Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence.Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromasp15(INK4b) plays a crucial role in murine lymphoid development and tumorigenesis.Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.Novel fluorescence in situ hybridization approaches in solid tumors. Characterization of frozen specimens, touch preparations, and cytological preparations.Capturing the molecular and biological diversity of high-grade astrocytoma in genetically engineered mouse modelsEFA (9-beta-D-erythrofuranosyladenine) is an effective salvage agent for methylthioadenosine phosphorylase-selective therapy of T-cell acute lymphoblastic leukemia with L-alanosine.Inhibition of Breast Tumor Cell Growth by Ectopic Expression of p16/INK4A Via Combined Effects of Cell Cycle Arrest, Senescence and Apoptotic Induction, and Angiogenesis InhibitionCorrelation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer.Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics.The CDKN2A (p16) gene and human cancer.
P2860
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P2860
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Deletion of p16 and p15 genes in brain tumors
@ast
Deletion of p16 and p15 genes in brain tumors
@en
Deletion of p16 and p15 genes in brain tumors
@nl
type
label
Deletion of p16 and p15 genes in brain tumors
@ast
Deletion of p16 and p15 genes in brain tumors
@en
Deletion of p16 and p15 genes in brain tumors
@nl
prefLabel
Deletion of p16 and p15 genes in brain tumors
@ast
Deletion of p16 and p15 genes in brain tumors
@en
Deletion of p16 and p15 genes in brain tumors
@nl
P2093
P50
P1433
P1476
Deletion of p16 and p15 genes in brain tumors
@en
P2093
J K Willson
J W Harper
N Papadopoulos
S H Bigner
S Markowitz
P304
P407
P577
1994-12-15T00:00:00Z