Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets - Wikidata - wikimedia - TriplyDB

Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

http://www.wikidata.org/entity/Q28244291

about

Molecular aspects of thyroid hormone actions G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization The role of peroxidation of mitochondrial membrane phospholipids in pancreatic β -cell failure Redox homeostasis in pancreatic β cells Mitochondrial regulation of β-cell function: maintaining the momentum for insulin release Physiological and pathological roles of mitochondrial SLC25 carriers A Mechanism for the Temporal Potentiation of Genipin to the Cytotoxicity of Cisplatin in Colon Cancer Cells Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.Genipin inhibits TNF-α-induced vascular smooth muscle cell proliferation and migration via induction of HO-1 The Hydroxyl at Position C1 of Genipin Is the Active Inhibitory Group that Affects Mitochondrial Uncoupling Protein 2 in Panc-1 Cells Hypoglycemic Activity and the Potential Mechanism of the Flavonoid Rich Extract from Sophora tonkinensis Gagnep. in KK-Ay Mice Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein.Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function.Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction Autoregulation of free radicals via uncoupling protein control in pancreatic beta-cell mitochondria.Uncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male mice Apoptosis induced by genipin in human leukemia K562 cells: involvement of c-Jun N-terminal kinase in G₂/M arrest.Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species.Mitochondrial flashes regulate ATP homeostasis in the heart.The regulation and turnover of mitochondrial uncoupling proteins.Glucose sensing in the pancreatic beta cell: a computational systems analysis.Transforming growth factor β₁ oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heart Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.Fatty acid flippase activity of UCP2 is essential for its proton transport in mitochondria.Leucine metabolism in regulation of insulin secretion from pancreatic beta cells.Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour.Genipin inhibits mitochondrial uncoupling protein 2 expression and ameliorates podocyte injury in diabetic mice.Glucose stimulation of hypothalamic MCH neurons involves K(ATP) channels, is modulated by UCP2, and regulates peripheral glucose homeostasis.Mitochondrial recoupling: a novel therapeutic strategy for cancer?Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion Mitochondrial dysfunction and β-cell failure in type 2 diabetes mellitus.Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells.Genipin suppresses NLRP3 inflammasome activation through uncoupling protein-2.Uncoupling protein 2 mediates resistance to gemcitabine-induced apoptosis in hepatocellular carcinoma cell lines.Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression.Glutathionylation state of uncoupling protein-2 and the control of glucose-stimulated insulin secretion.Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice

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P2860

Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets

http://www.wikidata.org/entity/Q28244291

description

2006 nî lūn-bûn

@nan

2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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type

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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J.CMET.2006.04.010

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Cell Metabolism

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Genipin inhibits UCP2-mediated ...... in isolated pancreatic islets

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Bradford B Lowell

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Chen-Yu Zhang

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Cheng-Ting Lin

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Chian Ping Ye

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John A Porco

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Laura E Parton

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Ruichao Shen

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Stefan Krauss

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417-27

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scholarly article

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16753577

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