Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy - Wikidata - wikimedia - TriplyDB

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy

http://www.wikidata.org/entity/Q28244992

about

Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin A novel custom resequencing array for dilated cardiomyopathy The Role of Leucine-Rich Repeat Containing Protein 10 (LRRC10) in Dilated Cardiomyopathy Mechanosensitive components of integrin adhesions: Role of vinculin Gap junction modulation and its implications for heart function Xin proteins and intercalated disc maturation, signaling and diseases Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart Cortactin is required for N-cadherin regulation of Kv1.5 channel function Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy New functions for alpha-catenins in health and disease: from cancer to heart regeneration Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.Drosophila PATJ supports adherens junction stability by modulating Myosin light chain activity.Integrins and integrin-associated proteins in the cardiac myocyte.Vinculin regulates osteoclast function What is vinculin needed for in platelets?Vinculin in cell-cell and cell-matrix adhesions.A mechanism of mechanotransduction at the cell-cell interface: emergence of α-catenin as the center of a force-balancing mechanism for morphogenesis in multicellular organisms.Mechanisms of gap junction traffic in health and disease Vinculin is indispensable for repopulation by hematopoietic stem cells, independent of integrin function.Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.Cardiomyocyte growth and sarcomerogenesis at the intercalated disc.Cell junctions in the specialized conduction system of the heart Mammalian enabled (Mena) is a critical regulator of cardiac function.Vinculin and talin: focus on the myocardium Coxsackievirus-induced miR-21 disrupts cardiomyocyte interactions via the downregulation of intercalated disk components.Mechanotransduction in cardiac hypertrophy and failure.New insights into vinculin function and regulation.An association between type Iγ PI4P 5-kinase and Exo70 directs E-cadherin clustering and epithelial polarization Determination of three-dimensional ventricular strain distributions in gene-targeted mice using tagged MRI α-Catenin uses a novel mechanism to activate vinculin.β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.The C-terminal tail domain of metavinculin, vinculin's splice variant, severs actin filaments.In Vivo Cannulation Methods for Cardiomyocytes Isolation from Heart Disease Models.Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior.Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function Cell-cell connection to cardiac disease

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P2860

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy

http://www.wikidata.org/entity/Q28244992

description

2007 nî lūn-bûn

@nan

2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

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name

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@ast

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@en

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@nl

type

label

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@ast

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@en

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@nl

prefLabel

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@ast

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@en

Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@nl

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Molecular and Cellular Biology

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Cardiac-myocyte-specific excis ...... eath or dilated cardiomyopathy

@en

P2093

Adam T Wright

http://www.w3.org/2001/XMLSchema#string

Alice E Zemljic-Harpf

http://www.w3.org/2001/XMLSchema#string

Ana Maria Manso

http://www.w3.org/2001/XMLSchema#string

Andrea K Thor

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Andrew D McCulloch

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Guy A Perkins

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Joel C Miller

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Laila Elsherif

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Nancy D Dalton

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Robert S Ross

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P2860

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

Vinculin--a dynamic regulator of cell adhesion

Complete sequence of human vinculin and assignment of the gene to chromosome 10

MAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.

Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.

Deconstructing the cadherin-catenin-actin complex

Re-solving the cadherin-catenin-actin conundrum

Immunolocalization of meta-vinculin in human smooth and cardiac muscles

Molecular heterogeneity of adherens junctions

Vinculin activation by talin through helical bundle conversion

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7522-37

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scholarly article

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4009940

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10.1128/MCB.00728-07

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21

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27

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2007-11-01T00:00:00Z

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17785437

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2169049

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