Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection - Wikidata - wikimedia - TriplyDB

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

http://www.wikidata.org/entity/Q28245039

about

Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning RNA-guided human genome engineering via Cas9 Targeting DNA With Fingers and TALENs Precision editing of large animal genomes Newer gene editing technologies toward HIV gene therapy A TALE of two nucleases: gene targeting for the masses?Genome-editing Technologies for Gene and Cell Therapy Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Enabling functional genomics with genome engineering Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools Designed nucleases for targeted genome editing Investigation of Rett syndrome using pluripotent stem cells Hematopoietic stem cell engineering at a crossroads Making designer mutants in model organisms Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9 Recent developments in human immunodeficiency virus-1 latency research Quantifying on- and off-target genome editing Gene therapy strategies for HIV/AIDS: preclinical modeling in humanized mice Homing endonucleases: DNA scissors on a mission Current translational and clinical practices in hematopoietic cell and gene therapy The tandem β-zipper: modular binding of tandem domains and linear motifs.The epigenome: the next substrate for engineering Chromatin regulation at the frontier of synthetic biology Engineering T Cells to Functionally Cure HIV-1 Infection Therapeutic genome editing: prospects and challenges Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification Current progress and challenges in HIV gene therapy CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering Improving CRISPR-Cas nuclease specificity using truncated guide RNAs High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.Efficient methods for targeted mutagenesis in zebrafish using zinc-finger nucleases: data from targeting of nine genes using CompoZr or CoDA ZFNs.Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing.High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity

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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

http://www.wikidata.org/entity/Q28245039

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Revealing off-target cleavage ...... ucleases by in vitro selection

@ast

Revealing off-target cleavage ...... ucleases by in vitro selection

@en

Revealing off-target cleavage ...... ucleases by in vitro selection

@nl

type

label

Revealing off-target cleavage ...... ucleases by in vitro selection

@ast

Revealing off-target cleavage ...... ucleases by in vitro selection

@en

Revealing off-target cleavage ...... ucleases by in vitro selection

@nl

prefLabel

Revealing off-target cleavage ...... ucleases by in vitro selection

@ast

Revealing off-target cleavage ...... ucleases by in vitro selection

@en

Revealing off-target cleavage ...... ucleases by in vitro selection

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Revealing off-target cleavage ...... ucleases by in vitro selection

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Cherie L Ramirez

http://www.w3.org/2001/XMLSchema#string

David R Liu

http://www.w3.org/2001/XMLSchema#string

J Keith Joung

http://www.w3.org/2001/XMLSchema#string

Vikram Pattanayak

http://www.w3.org/2001/XMLSchema#string

P2860

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5'-GNN-3' DNA target sequences

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

Primer3 on the WWW for general users and for biologist programmers

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

Unexpected failure rates for modular assembly of engineered zinc fingers

Targeted integration in rat and mouse embryos with zinc-finger nucleases

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765-70

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scholarly article

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3160628

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10.1038/NMETH.1670

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9

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8

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51552727

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1043918422

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21822273

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3164905

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