Targeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolism
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Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolismMitochondria, cholesterol and cancer cell metabolismGlutathione and mitochondriaBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsMLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 proteinMLN64 is involved in actin-mediated dynamics of late endocytic organelles.Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.STARTing to understand MLN64 function in cholesterol transport.Early steps in steroidogenesis: intracellular cholesterol trafficking.MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding siteInsights into the mechanisms of sterol transport between organelles.Niemann-Pick type C disease and intracellular cholesterol trafficking.Sterol transport in yeast and the oxysterol binding protein homologue (OSH) familyRole of the steroidogenic acute regulatory protein in health and disease.Lipid imbalance in the neurological disorder, Niemann-Pick C disease.Cholesterol and sphingolipids in alcohol-induced liver injury.Thirty-Eight-Year Follow-Up of Two Sibling Lipoid Congenital Adrenal Hyperplasia Patients Due to Homozygous Steroidogenic Acute Regulatory (STARD1) Protein Mutation. Molecular Structure and Modeling of the STARD1 L275P Mutation.Biliary cholesterol secretion: more than a simple ABC.Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function.Membrane Contact Sites: Complex Zones for Membrane Association and Lipid Exchange.Routes and mechanisms of post-endosomal cholesterol trafficking: A story that never ends.Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages.Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotypeMLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content.The role of endosomal cholesterol trafficking protein, StAR-related lipid transfer domain 3 (StarD3/MLN64), in BRIN-BD11 insulinoma cells.Serum cholestenoic acid as a potential marker of pulmonary cholesterol homeostasis: increased levels in patients with pulmonary alveolar proteinosis.Lysosomal and Mitochondrial Liaisons in Niemann-Pick Disease.Mitochondrial Cholesterol and the Paradox in Cell Death.Current knowledge on the acute regulation of steroidogenesis
P2860
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P2860
Targeted mutation of the MLN64 START domain causes only modest alterations in cellular sterol metabolism
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@ast
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@en
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@nl
type
label
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@ast
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@en
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@nl
prefLabel
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@ast
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@en
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@nl
P2093
P2860
P3181
P356
P1476
Targeted mutation of the MLN64 ...... in cellular sterol metabolism
@en
P2093
E Joan Blanchette-Mackie
Federico Martinez
Glenn L Radice
Igor Kostetskii
Jerome F Strauss
Nancy K Dwyer
Steven U Walkley
Tatsuro Kishida
Zhibing Zhang
P2860
P304
P3181
P356
10.1074/JBC.M400717200
P407
P577
2004-04-30T00:00:00Z