A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
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Cushing syndrome in pediatricsPhosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment responseHighly sensitive method for genomewide detection of allelic composition in nonpaired, primary tumor specimens by use of affymetrix single-nucleotide-polymorphism genotyping microarraysThe Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal HyperplasiaMolecular genetics of adrenocortical tumor formation and potential pharmacologic targetsCarney complex: an updateAlterations of Phosphodiesterases in Adrenocortical TumorsCREB--a real culprit in oncogenesis8-Chloro-cyclic AMP and protein kinase A I-selective cyclic AMP analogs inhibit cancer cell growth through different mechanismsGenetic predisposition to peripheral nerve neoplasia: diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromes[Absence of PRKAR1A loss of heterozygosity in laser-captured microdissected pigmented nodular adrenocortical tissue from a patient with Carney complex caused by the novel nonsense mutation p.Y21X].ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional ConsequencesACTH-independent Cushing's syndrome with bilateral micronodular adrenal hyperplasia and ectopic adrenocortical adenoma.The roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis.Familial micronodular adrenocortical disease, Cushing syndrome, and mutations of the gene encoding phosphodiesterase 11A4 (PDE11A).Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumorsIsolated familial somatotropinoma: 11q13-loh and gene/protein expression analysis suggests a possible involvement of aip also in non-pituitary tumorigenesisHaplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels.Regulation of steroidogenesis in a primary pigmented nodular adrenocortical disease-associated adenoma leading to virilization and subclinical Cushing's syndrome.Cyclic AMP, protein kinase A, and phosphodiesterases: proceedings of an international workshopPRKAR1A and the evolution of pituitary tumors.The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways.Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update.Mouse models of endocrine tumours.Familial testicular germ cell tumoursAdvances in targeting cyclic nucleotide phosphodiesterasesSolid tumors associated with multiple endocrine neoplasias.mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD).Carney complex and other conditions associated with micronodular adrenal hyperplasias.Copy number variants in short children born small for gestational age.Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype.Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer.How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?Rare and unusual endocrine cancer syndromes with mutated genes.Glucose-dependent insulinotropic peptide receptor overexpression in adrenocortical hyperplasia in MEN1 syndrome without loss of heterozygosity at the 11q13 locus.Cushing's syndrome secondary to isolated micronodular adrenocortical disease (iMAD) associated with rapid onset weight gain and negative abdominal MRI findings in a 3 year old male.Familial testicular germ cell tumors in adults: 2010 summary of genetic risk factors and clinical phenotype.Cushing syndrome caused by adrenocortical tumors and hyperplasias (corticotropin- independent Cushing syndrome)Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumorsCarney complex and lentiginosis
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P2860
A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
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2006 nî lūn-bûn
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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@ast
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@en
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
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type
label
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@ast
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@en
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@nl
prefLabel
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@ast
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@en
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@nl
P2093
P2860
P50
P3181
P356
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P1476
A genome-wide scan identifies ...... ith adrenocortical hyperplasia
@en
P2093
Amato Fratticci
Anelia Horvath
Christoforos Giatzakis
Elizabeth Levine
Georgia Delimpasi
Hui Pin Hsiao
Ioannis Bossis
J Aidan Carney
Kevin Cramer
Kurt J Griffin
P2860
P2888
P304
P3181
P356
10.1038/NG1809
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P50
P577
2006-07-01T00:00:00Z