Mechanisms of osteoclastogenesis inhibition by a novel class of biphenyl-type cannabinoid CB(2) receptor inverse agonists
about
Methylhonokiol attenuates neuroinflammation: a role for cannabinoid receptors?Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and DevelopmentThe natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonistsAmelioration of Cognitive Dysfunction in APP/PS1 Double Transgenic Mice by Long-Term Treatment of 4-O-Methylhonokiol.CB2 Cannabinoid receptors as a therapeutic target-what does the future hold?Trisubstituted Sulfonamides: a New Chemotype for Development of Potent and Selective CB2 Receptor Inverse Agonists.Antagonism of cannabinoid receptor 2 pathway suppresses IL-6-induced immunoglobulin IgM secretion.Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.4'-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation.Targeting cannabinoid receptor CB(2) in cardiovascular disorders: promises and controversies.Role of cannabinoids in the regulation of bone remodelingLead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitorsHonokiol analogs: a novel class of anticancer agents targeting cell signaling pathways and other bioactivities.The effect of endocannabinoid system in ischemia-reperfusion injury: a friend or a foe?Involvement of inflammation in Alzheimer's disease pathogenesis and therapeutic potential of anti-inflammatory agents.Functional selectivity at G-protein coupled receptors: Advancing cannabinoid receptors as drug targets.Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55.Cannabinoid CB1 and CB2 Receptor Signaling and BiasDivergent Reaction Pathways for Phenol Arylation by Arynes: Synthesis of Helicenes and 2-Arylphenols.Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway.Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models.4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice.Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against CCRF-CEM leukemia, U251 glioblastoma and HCT-116 colon cancer cells.
P2860
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P2860
Mechanisms of osteoclastogenesis inhibition by a novel class of biphenyl-type cannabinoid CB(2) receptor inverse agonists
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@ast
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@en
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@nl
type
label
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@ast
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@en
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@nl
prefLabel
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@ast
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@en
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@nl
P2093
P921
P1476
Mechanisms of osteoclastogenes ...... B(2) receptor inverse agonists
@en
P2093
Antje Huefner
Jonas Kleyer
Juan Manuel Viveros Paredes
Jürg Gertsch
Karl-Heinz Altmann
Stefan Raduner
Wolfgang Schuehly
P304
P356
10.1016/J.CHEMBIOL.2011.05.012
P407
P577
2011-08-01T00:00:00Z