The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants
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Mitochondrial DNA mutations in human diseaseMitochondrial Dysfunction in Cancer and Neurodegenerative Diseases: Spotlight on Fatty Acid Oxidation and Lipoperoxidation ProductsMitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?Microscale oxygraphy reveals OXPHOS impairment in MRC mutant cellsAlleviation of neuronal energy deficiency by mTOR inhibition as a treatment for mitochondria-related neurodegenerationA mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicineCentral nervous system manifestations of mitochondrial disorders.Interaction of cyanide and nitric oxide with cytochrome c oxidase: implications for acute cyanide toxicity.Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects.Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies.The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility.Hereditary spastic paraplegia: clinico-pathologic features and emerging molecular mechanisms.mtDNA mutations increase tumorigenicity in prostate cancer.A yeast-based assay identifies drugs active against human mitochondrial disordersMitochondrial ATP synthase: architecture, function and pathology.Gene therapy for the treatment of mitochondrial DNA disorders.Aging: A mitochondrial DNA perspective, critical analysis and an update.Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutantCurrent experience in testing mitochondrial nutrients in disorders featuring oxidative stress and mitochondrial dysfunction: rational design of chemoprevention trials.Analysis of mitochondrial ND1 gene in human colorectal cancerMitochondrial protein sorting as a therapeutic target for ATP synthase disorders.Electric field driven torque in ATP synthase.Is there more to aging than mitochondrial DNA and reactive oxygen species?mtDNA T8993G mutation-induced F1F0-ATP synthase defect augments mitochondrial dysfunction associated with hypoxia/reoxygenation: the protective role of melatoninGlucose modulation induces reactive oxygen species and increases P-glycoprotein-mediated multidrug resistance to chemotherapeutics.Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies.Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition.The mitochondrial respiratory chain is a modulator of apoptosis.The role of mitochondria in inherited neurodegenerative diseases.Mitochondria and cancer: Warburg addressed.Cytochrome c oxidase biogenesis: new levels of regulationRespiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency.Synthesis of cytochrome c oxidase subunit 1 is translationally downregulated in the absence of functional F1F0-ATP synthase.The mitochondrial brain: From mitochondrial genome to neurodegenerationScreening of mitochondrial mutations in Tunisian patients with mitochondrial disorders: an overview study.Heteroplasmic shifts in tumor mitochondrial genomes reveal tissue-specific signals of relaxed and positive selection.Loss of LRPPRC causes ATP synthase deficiencyWeigh and wait: the prospect of mitochondrial gene replacement.mtDNA T8993G mutation-induced mitochondrial complex V inhibition augments cardiolipin-dependent alterations in mitochondrial dynamics during oxidative, Ca(2+), and lipid insults in NARP cybrids: a potential therapeutic target for melatonin.Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani.
P2860
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P2860
The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@ast
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@en
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@nl
type
label
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@ast
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@en
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@nl
prefLabel
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@ast
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@en
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@nl
P2093
P3181
P356
P1476
The mtDNA T8993G (NARP) mutati ...... an be improved by antioxidants
@en
P2093
Carl D Gajewski
Chetan Vijayvergiya
Darryl C DeVivo
Giorgio Lenaz
Giovanni Manfredi
Marina Mattiazzi
Martin Wiedmann
P304
P3181
P356
10.1093/HMG/DDH103
P407
P577
2004-04-15T00:00:00Z