Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization
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Swapping the substrate specificities of the neuropeptidases neurolysin and thimet oligopeptidaseThe Exquisite Structure and Reaction Mechanism of Bacterial Pz-peptidase A toward Collagenous Peptides: X-RAY CRYSTALLOGRAPHIC STRUCTURE ANALYSIS OF PZ-PEPTIDASE A REVEALS DIFFERENCES FROM MAMMALIAN THIMET OLIGOPEPTIDASEStructure of theArabidopsis thalianaTOP2 oligopeptidaseNeurolysin knockout mice generation and initial phenotype characterizationHormonal regulation of female reproduction.The role of Tyr605 and Ala607 of thimet oligopeptidase and Tyr606 and Gly608 of neurolysin in substrate hydrolysis and inhibitor bindingTwo thimet oligopeptidase-like Pz peptidases produced by a collagen-degrading thermophile, Geobacillus collagenovorans MO-1.Redox modulation of thimet oligopeptidase activity by hydrogen peroxideIdentification and characterization of Aβ peptide interactors in Alzheimer's disease by structural approaches.Allosteric inhibition of the neuropeptidase neurolysin.Characterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth.An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.MHC class I alleles and their exploration of the antigen-processing machinery.Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment.EP24.15 as a Potential Regulator of Kisspeptin Within the Neuroendocrine Hypothalamus.A proposed role for Leishmania major carboxypeptidase in peptide catabolismHydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selectionOrganellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor.Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells.Intracellular peptides as natural regulators of cell signaling.Crystallization and preliminary X-ray crystallographic analysis of Pz peptidase B from Geobacillus collagenovorans MO-1.Crystallization and preliminary X-ray crystallographic studies of Pz peptidase A from Geobacillus collagenovorans MO-1.Two metallocarboxypeptidases from the protozoan Trypanosoma cruzi belong to the M32 family, found so far only in prokaryotes.Flexibility in substrate recognition by thimet oligopeptidase as revealed by denaturation studies.14-3-3 epsilon modulates the stimulated secretion of endopeptidase 24.15.Size matters for the tripeptidylpeptidase II complex from Drosophila: The 6-MDa spindle form stabilizes the activated state.N-Gemini peptides: cytosolic protease resistance via N-terminal dimerization of unstructured peptides.
P2860
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P2860
Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Crystal structure of human thi ...... , regulation, and localization
@ast
Crystal structure of human thi ...... , regulation, and localization
@en
Crystal structure of human thi ...... , regulation, and localization
@nl
type
label
Crystal structure of human thi ...... , regulation, and localization
@ast
Crystal structure of human thi ...... , regulation, and localization
@en
Crystal structure of human thi ...... , regulation, and localization
@nl
prefLabel
Crystal structure of human thi ...... , regulation, and localization
@ast
Crystal structure of human thi ...... , regulation, and localization
@en
Crystal structure of human thi ...... , regulation, and localization
@nl
P2093
P2860
P356
P1476
Crystal structure of human thi ...... , regulation, and localization
@en
P2093
Christina S Hines
David W Rodgers
Jerry Coll-Rodriguez
Kallol Ray
P2860
P304
P356
10.1074/JBC.M400795200
P407
P577
2004-05-07T00:00:00Z