A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
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The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritisRecent Insights Into the Genetics of Inflammatory Bowel DiseaseGenome-wide association defines more than 30 distinct susceptibility loci for Crohn's diseaseControl of vesicle fusion by a tyrosine phosphataseStructure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseasesIdentification of substrates of human protein-tyrosine phosphatase PTPN22Identification of a variant form of tyrosine phosphatase LYPSubstrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrateCutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signalingGenome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsFoxp3 occupancy and regulation of key target genes during T-cell stimulationAutoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residueGenome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetesA candidate gene study of CLEC16A does not provide evidence of association with risk for anti-CCP-positive rheumatoid arthritisA human type 1 diabetes susceptibility locus maps to chromosome 21q22.3Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetesThe CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the futureA haplotype map of the human genomeT1DBase, a community web-based resource for type 1 diabetes researchRheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allelePolymorphism discovery and association analyses of the interferon genes in type 1 diabetesThe role for protein tyrosine phosphatase non-receptor type 22 in regulating intestinal homeostasisAutoimmune diseases - connecting risk alleles with molecular traits of the immune system.The Role of Gluten in Celiac Disease and Type 1 DiabetesCellular biochemistry methods for investigating protein tyrosine phosphatasesMechanisms of autoimmune thyroid diseases: from genetics to epigeneticsSmall molecule tools for functional interrogation of protein tyrosine phosphatasesGenetics of type 1 diabetesB cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody productionA functional framework for interpretation of genetic associations in T1DCurrent aspects of vitiligo geneticsRisk factors and primary prevention trials for type 1 diabetesInsights into type 1 diabetes from the autoimmune polyendocrine syndromesEffect of genetic factors on the association between coronary artery disease and PTPN22 polymorphismThymus, innate immunity and autoimmune arthritis: interplay of gene and environmentRethinking mechanisms of autoimmune pathogenesisCrystal Structure of the Human Lymphoid Tyrosine Phosphatase Catalytic Domain: Insights into Redox Regulation,A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune DiseasesRheumatoid arthritis: identifying and characterising polymorphisms using rat modelsAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune Diseases
P2860
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P2860
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@ast
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@en
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@nl
type
label
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@ast
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@en
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@nl
prefLabel
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@ast
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@en
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
@en
P2093
David Comings
George S Eisenbarth
Gian Franco Meloni
James MacMurray
Konstantina Nika
Lucia Musumeci
Masoud Rostamkhani
Paola Lucarelli
Souad Rahmouni
Tomas Mustelin
P2860
P2888
P3181
P356
10.1038/NG1323
P407
P577
2004-04-01T00:00:00Z
P5875
P6179
1017486558