Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
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Recent progress on C-4-modified podophyllotoxin analogs as potent antitumor agentsNovel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding SiteIdentification of therapeutic candidates for chronic lymphocytic leukemia from a library of approved drugsCompound A398, a novel podophyllotoxin analogue: cytotoxicity and induction of apoptosis in human leukemia cellsAlleviation of podophyllotoxin toxicity using coexisting flavonoids from Dysosma versipellis.Structural simplification of bioactive natural products with multicomponent synthesis: dihydropyridopyrazole analogues of podophyllotoxinSeven-Membered Lactam Derivatives of Podophyllotoxins as New Pesticidal Agents.Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis.Synthetic and application perspectives of azapodophyllotoxins: alternative scaffolds of podophyllotoxin.Intramolecular dehydro-Diels-Alder reaction affords selective entry to arylnaphthalene or aryldihydronaphthalene lignansMiR-181b sensitizes glioma cells to teniposide by targeting MDM2.Transcriptome sequencing of rhizome tissue of Sinopodophyllum hexandrum at two temperatures.Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNAA highly tumor-targeted nanoparticle of podophyllotoxin penetrated tumor core and regressed multidrug resistant tumors.Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIα Catalytic Inhibitors.Structure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogsN-hydroxyethyl-4-aza-didehydropodophyllotoxin derivatives as potential antitumor agents.Insight into 2α-Chloro-2'(2',6')-(Di)Halogenopicropodophyllotoxins Reacting with Carboxylic Acids Mediated by BF3·Et2O.Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin.Recent Progress of Research on Herbal Products Used in Traditional Chinese Medicine: the Herbs belonging to The Divine Husbandman's Herbal Foundation Canon ( Shén Nóng Běn Cǎo Jīng).Updated biotechnological approaches developed for 2,7'-cyclolignan production1.Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives.Cell cycle modulatory and apoptotic effects of plant-derived anticancer drugs in clinical use or development.Podophyllotoxin derivatives: a patent review (2012 - 2014).The potential of combi-molecules with DNA-damaging function as anticancer agents.Cytotoxic activity of a synthetic deoxypodophyllotoxin derivative with an opened D-ring.Biotechnological interventions for harnessing podophyllotoxin from plant and fungal species: current status, challenges, and opportunities for its commercialization.Synthesis and Evaluation of New Podophyllotoxin Derivatives with in Vitro Anticancer Activity.Novel capsaicin analogues as potential anticancer agents: synthesis, biological evaluation, and in silico approach.Natural compounds with P2X7 receptor-modulating properties.Analgesic and anti-inflammatory activity of podophyllotoxin derivatives.Synthesis and cytotoxicity evaluation of novel podophyllotoxin derivatives.D11, a novel glycosylated diphyllin derivative, exhibits potent anticancer activity by targeting topoisomerase IIα.Novel 4 beta-anilino-podophyllotoxin derivatives: design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents.Stereoselective synthesis of 4α-alkyloxy-2-α/β-bromopodophyllotoxin derivatives as insecticidal agents.High-resolution phenotypic profiling of natural products-induced effects on the single-cell level.Reengineered epipodophyllotoxin.OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells.Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma.Phytochemical based nanomedicines against cancer: current status and future prospects.
P2860
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P2860
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
description
2005 nî lūn-bûn
@nan
2005 թուականին հրատարակուած գիտական յօդուած
@hyw
2005 թվականին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@ast
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@en
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@nl
type
label
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@ast
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@en
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@nl
prefLabel
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@ast
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@en
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@nl
P356
P1476
Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents
@en
P304
P356
10.2174/1381612053764724
P407
P50
P577
2005-01-01T00:00:00Z