Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation

Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation

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http://www.wikidata.org/entity/Q28250665

Q28250665

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A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis Early events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cells Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1 Cigarette smoke-induced pancreatic damage: experimental data.Lung carcinoma signaling pathways activated by smoking.Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells.Upregulation of nuclear factor-kappaB expression by SLURP-1 is mediated by alpha7-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases.Epigenetic effects and molecular mechanisms of tumorigenesis induced by cigarette smoke: an overview NNK, a tobacco-specific carcinogen, inhibits the expression of lysyl oxidase, a tumor suppressor.From smoking to cancers: novel targets to neuronal nicotinic acetylcholine receptors.RUNX transcription factors: association with pediatric asthma and modulated by maternal smoking.4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes esophageal squamous cell carcinoma growth via beta-adrenoceptors in vitro and in vivo Green tea catechin extract in intervention of chronic breast cell carcinogenesis induced by environmental carcinogens.Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis.Nitrosamines as nicotinic receptor ligands Lipopolysaccharide enhances mouse lung tumorigenesis: a model for inflammation-driven lung cancer.Regulation of the G1/S phase of the cell cycle and alterations in the RB pathway in human lung cancer.The pharmokinetic limitations of antioxidant treatment for COPD.Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma Sensitivity to NNKOAc is associated with renal cancer risk.Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy.Tobacco carcinogen NNK-induced lung cancer animal models and associated carcinogenic mechanisms.Comparison of in vitro toxicological effects of biomass smoke from different sources of animal dung.The α7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to taxanes.Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells.4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro.Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease.Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells.Alpha5 Nicotinic Acetylcholine Receptor Contributes to Nicotine-Induced Lung Cancer Development and Progression.Receptor-mediated tobacco toxicity: alterations of the NF-kappaB expression and activity downstream of alpha7 nicotinic receptor in oral keratinocytes NF-kappaB in lung tumorigenesis.Airway administration of vascular endothelial growth factor siRNAs induces transient airspace enlargement in mice.α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro.Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells.Single-nucleotide polymorphisms of LIG1 associated with risk of lung cancer.Genetic single-nucleotide polymorphisms of inflammation-related factors associated with risk of lung cancer.Quantitative assessment of the influence of common variations (rs8034191 and rs1051730) at 15q25 and lung cancer risk.

P2860

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P2860

Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation

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http://www.wikidata.org/entity/Q28250665

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2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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