Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion
about
Survivin: a unique target for tumor therapyTargeting survivin in cancer therapyIFN-γ upregulates survivin and Ifi202 expression to induce survival and proliferation of tumor-specific T cells.Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo.T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment.Control of immunity by the TNFR-related molecule OX40 (CD134)Differential requirements for survivin in hematopoietic cell development.Apoptosis and the homeostatic control of immune responses.Claudin 13, a member of the claudin family regulated in mouse stress induced erythropoiesisActivation of Fms-like tyrosine kinase 3 signaling enhances survivin expression in a mouse model of rheumatoid arthritisOX40 costimulation can abrogate Foxp3+ regulatory T cell-mediated suppression of antitumor immunity.Altered T cell responses in children with autism.Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cellsSurvivin modulates genes with divergent molecular functions and regulates proliferation of hematopoietic stem cells through Evi-1Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy.OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.Regulation of A1 by OX40 contributes to CD8(+) T cell survival and anti-tumor activity.The significance of OX40 and OX40L to T-cell biology and immune disease.The human immunodeficiency virus protease inhibitor ritonavir inhibits lung cancer cells, in part, by inhibition of survivin.Inhibition of survivin influences the biological activities of canine histiocytic sarcoma cell lines.Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis.CD127+CCR5+CD38+++ CD4+ Th1 effector cells are an early component of the primary immune response to vaccinia virus and precede development of interleukin-2+ memory CD4+ T cells.Novel insights into the regulatory architecture of CD4+ T cells in rheumatoid arthritisRole of the Survivin gene in pathophysiologyActivation of OX40 prolongs and exacerbates autoimmune experimental uveitisRole of co-stimulation in LeishmaniasisPD-1 Co-inhibitory and OX40 Co-stimulatory Crosstalk Regulates Helper T Cell Differentiation and Anti-Plasmodium Humoral Immunity.Nitric oxide induces CD4+CD25+ Foxp3 regulatory T cells from CD4+CD25 T cells via p53, IL-2, and OX40Programming of regulatory T cells from pluripotent stem cells and prevention of autoimmunity.Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice.C-Myc regulation by costimulatory signals modulates the generation of CD8+ memory T cells during viral infection.Essential Role for Survivin in the Proliferative Expansion of Progenitor and Mature B Cells.Increased levels of survivin, via association with heat shock protein 90, in mucosal T cells from patients with Crohn's disease.Tumor-released survivin induces a type-2 t cell response and decreases cytotoxic T cell function, in vitro.Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival.A novel differentiation pathway from CD4⁺ T cells to CD4⁻ T cells for maintaining immune system homeostasisThe TNF Receptor Superfamily in Co-stimulating and Co-inhibitory ResponsesCasitas B-lineage lymphoma b inhibits antigen recognition and slows cell cycle progression at late times during CD4+ T cell clonal expansion.Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from survivin and that from its splice variant survivin-2B in oral cancer patients.IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.
P2860
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P2860
Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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name
Sustained survivin expression ...... drives T cell clonal expansion
@ast
Sustained survivin expression ...... drives T cell clonal expansion
@en
Sustained survivin expression ...... drives T cell clonal expansion
@nl
type
label
Sustained survivin expression ...... drives T cell clonal expansion
@ast
Sustained survivin expression ...... drives T cell clonal expansion
@en
Sustained survivin expression ...... drives T cell clonal expansion
@nl
prefLabel
Sustained survivin expression ...... drives T cell clonal expansion
@ast
Sustained survivin expression ...... drives T cell clonal expansion
@en
Sustained survivin expression ...... drives T cell clonal expansion
@nl
P2093
P3181
P1433
P1476
Sustained survivin expression ...... drives T cell clonal expansion
@en
P2093
Jianxun Song
Mary Cheng
Michael Croft
Xiaohong Tang
P304
P3181
P356
10.1016/J.IMMUNI.2005.03.012
P407
P50
P577
2005-05-01T00:00:00Z