Identification and characterization of cellular receptors for the growth regulator, oncostatin M
about
Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6Cleavage of a hydrophilic C-terminal domain increases growth-inhibitory activity of oncostatin MMolecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin MAIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodiesOncostatin M binds to extracellular matrix in a bioactive conformation: implications for inflammation and metastasisOncostatin M is a mitogen for rabbit vascular smooth muscle cellsOncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules.Evaluation and optimization of hepatocyte culture media factors by design of experiments (DoE) methodology.A computer simulation approach to assessing therapeutic intervention points for the prevention of cytokine-induced cartilage breakdown.Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42MAPK/ERK-2 in Kaposi's cells. Evidence that this pathway is important in Kaposi cell growth.
P2860
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P2860
Identification and characterization of cellular receptors for the growth regulator, oncostatin M
description
1989 nî lūn-bûn
@nan
1989 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մարտին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Identification and characteriz ...... growth regulator, oncostatin M
@ast
Identification and characteriz ...... growth regulator, oncostatin M
@en
Identification and characteriz ...... growth regulator, oncostatin M
@nl
type
label
Identification and characteriz ...... growth regulator, oncostatin M
@ast
Identification and characteriz ...... growth regulator, oncostatin M
@en
Identification and characteriz ...... growth regulator, oncostatin M
@nl
prefLabel
Identification and characteriz ...... growth regulator, oncostatin M
@ast
Identification and characteriz ...... growth regulator, oncostatin M
@en
Identification and characteriz ...... growth regulator, oncostatin M
@nl
P2093
P1476
Identification and characteriz ...... growth regulator, oncostatin M
@en
P2093
J C Kallestad
J M Zarling
M Bolton-Hanson
P S Linsley
P304
P407
P577
1989-03-15T00:00:00Z