Tying it all together: epigenetics, genetics, cell cycle, and cancer
about
Cloning of a mammalian transcriptional activator that binds unmethylated CpG motifs and shares a CXXC domain with DNA methyltransferase, human trithorax, and methyl-CpG binding domain protein 1.Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis.Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissuesFrequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinomaEffects of histone acetylation and DNA methylation on p21( WAF1) regulationPCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNAPCNA binding through a conserved motifA cascade of modules of a network defines cancer progressionControl of RNA polymerase I-directed transcription: recent trends.Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylationDevelopmental programming of fetal skeletal muscle and adipose tissue development.Transcriptional repression by Drosophila methyl-CpG-binding proteins.Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation databaseAlteration of DNA methylation in gastrointestinal carcinogenesis.Label-free electrochemical detection of human methyltransferase from tumors.Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancersEpigenetics in prostate cancer.Folic acid food fortification-its history, effect, concerns, and future directionsDNA methylation regulates p27kip1 expression in rodent pituitary cell lines.Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis.Epigenetic alterations in gastric carcinogenesis.Evidence for gene silencing by endogenous DNA methylation.Developmental genes significantly afflicted by aberrant promoter methylation and somatic mutation predict overall survival of late-stage colorectal cancer.Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients.Detection of replicative integrity in small colonic biopsies using the BrdUrd comet assay.CpG island methylation in familial colorectal cancer patients not fulfilling the Amsterdam criteria.The effect of 1 mg folic acid supplementation on clinical outcomes in female migraine with aura patients.Current progress in epigenetic research for hepatocarcinomagenesis.Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases.The biology of the sodium iodide symporter and its potential for targeted gene delivery.New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy.DNA methylation and cancer development: molecular mechanism.Ethanol alters proliferation and differentiation of normal and chromosomally abnormal human embryonic stem cell-derived neurospheres.Aberrant gene promoter methylation of E-cadherin, p16 INK4a , p14 ARF , and MGMT in Epstein-Barr virus-associated oral squamous cell carcinomas.Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.Cytosine methylation of an Sp1 site contributes to organ-specific and cell-specific regulation of expression of the lung epithelial gene t1alpha.Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation.DNA methylation pattern in mouse oocytes and their in vitro fertilized early embryos: effect of oocyte vitrification.Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation.5-AZA-2'-deoxycytidine (5-AZA-CdR) leads to down-regulation of Dnmt1o and gene expression in preimplantation mouse embryos.
P2860
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P2860
Tying it all together: epigenetics, genetics, cell cycle, and cancer
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@ast
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@en
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@nl
type
label
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@ast
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@en
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@nl
prefLabel
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@ast
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@en
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@nl
P2860
P3181
P1433
P1476
Tying it all together: epigenetics, genetics, cell cycle, and cancer
@en
P2093
S B Baylin
P2860
P304
P3181
P356
10.1126/SCIENCE.277.5334.1948
P407
P577
1997-09-26T00:00:00Z