Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
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The Nodal signaling pathway controls left-right asymmetric development in amphioxusNodal morphogensDirect and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heartPitx2 is a critical early regulatory gene in normal cecal developmentThe Zic2 gene directs the formation and function of node cilia to control cardiac situsDysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organismsThe pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse modelCoordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevisShroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesisPotential novel mechanism for Axenfeld-Rieger syndrome: deletion of a distant region containing regulatory elements of PITX2The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine.Long-range regulatory interactions at the 4q25 atrial fibrillation risk locus involve PITX2c and ENPEP.Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1.Hyperglycemia impairs left-right axis formation and thereby disturbs heart morphogenesis in mouse embryos.BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4.A right-sided pathway involving FGF8/Snai1 controls asymmetric development of the proepicardium in the chick embryo.Utility and limits of Hprt-Cre technology in generating mutant mouse embryos.HCN4 ion channel function is required for early events that regulate anatomical left-right patterning in a Nodal- and Lefty asymmetric gene expression-independent manner.Mechanism responsible for D-transposition of the great arteries: Is this part of the spectrum of right isomerism?Left-Right Patterning: Breaking Symmetry to Asymmetric Morphogenesis.Chromatin Architecture of the Pitx2 Locus Requires CTCF- and Pitx2-Dependent Asymmetry that Mirrors Embryonic Gut Laterality.Altered paracrine signaling from the injured knee joint impairs postnatal long bone growthMutations in zebrafish pitx2 model congenital malformations in Axenfeld-Rieger syndrome but do not disrupt left-right placement of visceral organs.The chirality of gut rotation derives from left-right asymmetric changes in the architecture of the dorsal mesentery.Nuclear factor 1 and T-cell factor/LEF recognition elements regulate Pitx2 transcription in pituitary development.Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos.Current Perspectives in Cardiac Laterality.Vertebrate Left-Right Asymmetry: What Can Nodal Cascade Gene Expression Patterns Tell Us?PITX2 DNA-methylation predicts response to anthracycline-based adjuvant chemotherapy in triple-negative breast cancer patients.Ancient homeobox gene loss and the evolution of chordate brain and pharynx development: deductions from amphioxus gene expression.Embryonic left-right separation mechanism allows confinement of mutation-induced phenotypes to one lateral body half of bilaterians.Left Right Patterning, Evolution and Cardiac Development.Some Isolated Cardiac Malformations Can Be Related to Laterality Defects.Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice.
P2860
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P2860
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
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2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@ast
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@en
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@nl
type
label
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@ast
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@en
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@nl
prefLabel
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@ast
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@en
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@nl
P2093
P356
P1433
P1476
Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs
@en
P2093
Hidetaka Shiratori
Hiroshi Hamada
Kenta Yashiro
P304
P356
10.1242/DEV.02470
P407
P577
2006-08-01T00:00:00Z