A novel enzyme from bovine neurointermediate pituitary catalyzes dealkylation of alpha-hydroxyglycine derivatives, thereby functioning sequentially with peptidylglycine alpha-amidating monooxygenase in peptide amidation
about
Peptidylglycine alpha-amidating monooxygenase: a multifunctional protein with catalytic, processing, and routing domains60 YEARS OF POMC: From POMC and α-MSH to PAM, molecular oxygen, copper, and vitamin CEvidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunnelingKinetic and stereochemical studies on novel inactivators of C-terminal amidationUbiquitin and ubiquitin-derived peptides as substrates for peptidylglycine alpha-amidating monooxygenaseImmunocytochemical mapping of the amidating enzyme PAM in the developing and adult mouse lungImino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine alpha-hydroxylating monooxygenase.Primary structure of the precursor for the sea anemone neuropeptide Antho-RFamide (less than Glu-Gly-Arg-Phe-NH2).Inhibition of JNK and p38 MAPK phosphorylation by 5-(acetylamino)-4-oxo-6-phenyl-2-hexenoic acid methyl ester and 4-phenyl-butenoic acid decreases substance P-induced TNF-α upregulation in macrophagesCOOH-terminal signals mediate the trafficking of a peptide processing enzyme in endocrine cellsProduction of the catalytic core of human peptidylglycine α-hydroxylating monooxygenase (hPHMcc) in Escherichia coliStopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase.Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid.Manufacturing peptides as active pharmaceutical ingredients.Post-translational N-glycosylation of a truncated form of a peptide processing enzyme.Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs.Addition of an endoplasmic reticulum retention/retrieval signal does not block maturation of enzymatically active peptidylglycine alpha-amidating monooxygenase.Expression of individual forms of peptidylglycine alpha-amidating monooxygenase in AtT-20 cells: endoproteolytic processing and routing to secretory granules.Kinetic isotope effects of peptidylglycine alpha-hydroxylating mono-oxygenase reaction.The source of the oxygen atom in the alpha-hydroxyglycine intermediate of the peptidylglycine alpha-amidating reaction.Kinetic and inhibition studies on substrate channelling in the bifunctional enzyme catalysing C-terminal amidationNN-dimethyl-1,4-phenylenediamine as an alternative reductant for peptidylglycine alpha-amidating mono-oxygenase catalysisCatalysis, stereochemistry, and inhibition of ureidoglycolate lyase.Neurosecretory vesicles contain soluble and membrane-associated monofunctional and bifunctional peptidylglycine alpha-amidating monooxygenase proteins.Role for an essential tyrosine in peptide amidation.
P2860
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P2860
A novel enzyme from bovine neurointermediate pituitary catalyzes dealkylation of alpha-hydroxyglycine derivatives, thereby functioning sequentially with peptidylglycine alpha-amidating monooxygenase in peptide amidation
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@ast
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@en
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@nl
type
label
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@ast
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@en
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@nl
prefLabel
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@ast
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@en
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@nl
P2093
P356
P1433
P1476
A novel enzyme from bovine neu ...... oxygenase in peptide amidation
@en
P2093
P304
P356
10.1021/BI00478A001
P407
P577
1990-07-03T00:00:00Z