Disruption of a brain transcription factor, NPAS3, is associated with schizophrenia and learning disability
about
A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expressionDiscovery of a proneurogenic, neuroprotective chemicalIsolation and Characterization of Chicken NPAS3Expression of NPAS3 in the human cortex and evidence of its posttranscriptional regulation by miR-17 during development, with implications for schizophreniaThe NPAS3 gene--emerging evidence for a role in psychiatric illnessInteracting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorderCross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depressionGene expression in cortical interneuron precursors is prescient of their mature function.The myelin-pathogenesis puzzle in schizophrenia: a literature review.Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p.Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depressionNPAS3 variants in schizophrenia: a neuroimaging study.Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.Rare structural variants in schizophrenia: one disorder, multiple mutations; one mutation, multiple disordersCytogenetics and gene discovery in psychiatric disorders.Genetic associations with brain cortical thickness in multiple sclerosisBasic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilitiesSchizopsychotic symptom-profiles and biomarkers: beacons in diagnostic labyrinths.Chromosome abnormalities, mental retardation and the search for genes in bipolar disorder and schizophrenia.Can the role of genetic factors in schizophrenia be enlightened by studies of candidate gene mutant mice behaviour?Progress in defining the biological causes of schizophrenia.Disorders and borders: psychiatric genetics and nosology.Adult Neurogenesis and Psychiatric Disorders.Transcriptional regulation of neurodevelopmental and metabolic pathways by NPAS3.The developmental brain gene NPAS3 contains the largest number of accelerated regulatory sequences in the human genome.A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation.A fast-evolving human NPAS3 enhancer gained reporter expression in the developing forebrain of transgenic mice.Evolution, functional divergence and conserved exon-intron structure of bHLH/PAS gene family.Human accelerated regions and other human-specific sequence variations in the context of evolution and their relevance for brain development.Cumulative role of rare and common putative functional genetic variants at NPAS3 in schizophrenia susceptibility.Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder.Partial tetrasomy 14 associated with multiple malformations.SOX11 target genes: implications for neurogenesis and neuropsychiatric illness.Risks and Recommendations in Prenatally Detected De Novo Balanced Chromosomal Rearrangements from Assessment of Long-Term Outcomes
P2860
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P2860
Disruption of a brain transcription factor, NPAS3, is associated with schizophrenia and learning disability
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Disruption of a brain transcri ...... hrenia and learning disability
@ast
Disruption of a brain transcri ...... hrenia and learning disability
@en
Disruption of a brain transcri ...... hrenia and learning disability
@nl
type
label
Disruption of a brain transcri ...... hrenia and learning disability
@ast
Disruption of a brain transcri ...... hrenia and learning disability
@en
Disruption of a brain transcri ...... hrenia and learning disability
@nl
prefLabel
Disruption of a brain transcri ...... hrenia and learning disability
@ast
Disruption of a brain transcri ...... hrenia and learning disability
@en
Disruption of a brain transcri ...... hrenia and learning disability
@nl
P2093
P921
P356
P1476
Disruption of a brain transcri ...... hrenia and learning disability
@en
P2093
Ben S Pickard
D H R Blackwood
D J Porteous
M P Malloy
P356
10.1002/AJMG.B.30204
P407
P577
2005-07-05T00:00:00Z