Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family
about
The human protein disulfide isomerase gene familyThe protein disulfide isomerase AGR2 is essential for production of intestinal mucusEpidermal growth factor receptor (EGFR) signaling requires a specific endoplasmic reticulum thioredoxin for the post-translational control of receptor presentation to the cell surfaceDifferential expression of anterior gradient gene AGR2 in prostate cancerThe estrogen-responsive Agr2 gene regulates mammary epithelial proliferation and facilitates lobuloalveolar developmentMolecular basis for the nerve dependence of limb regeneration in an adult vertebrateSPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus productionProtein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].Zebrafish Agr2 is required for terminal differentiation of intestinal goblet cellsNeuroD1 is required for survival of photoreceptors but not pinealocytes: results from targeted gene deletion studies.AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and DThe Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set.Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells.Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survivalThe human adenocarcinoma-associated gene, AGR2, induces expression of amphiregulin through Hippo pathway co-activator YAP1 activationAGR3 in breast cancer: prognostic impact and suitable serum-based biomarker for early cancer detection.Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis.Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia.New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in MiceThe Endoplasmic Reticulum Resident Protein AGR3. Required for Regulation of Ciliary Beat Frequency in the Airway.The metastasis-inducing protein AGR2 is O-glycosylated upon secretion from mammary epithelial cells.AGR2 is associated with gastric cancer progression and poor survival.The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarkerSecretion of protein disulphide isomerase AGR2 confers tumorigenic propertiesEmerging roles for the pro-oncogenic anterior gradient-2 in cancer development.Ras-dva1 small GTPase regulates telencephalon development in Xenopus laevis embryos by controlling Fgf8 and Agr signaling at the anterior border of the neural plate.Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2.Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype.Proteomic study explores AGR2 as pro-metastatic protein in HCC.2,3,7,8-tetrachlorodibenzo-p-dioxin counteracts the p53 response to a genotoxicant by upregulating expression of the metastasis marker agr2 in the hepatocarcinoma cell line HepG2.Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition.The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio.Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2-/- mice.Agr genes, missing in amniotes, are involved in the body appendages regeneration in frog tadpoles.Emerging roles of protein disulfide isomerase in cancer.Factors controlling sperm migration through the oviduct revealed by gene-modified mouse models.The sequence-specific peptide-binding activity of the protein sulfide isomerase AGR2 directs its' stable binding to the oncogenic receptor EpCAM.Anterior gradient 2 and 3--two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells.Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells.
P2860
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P2860
Diversity of the protein disulfide isomerase family: identification of breast tumor induced Hag2 and Hag3 as novel members of the protein family
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Diversity of the protein disul ...... members of the protein family
@ast
Diversity of the protein disul ...... members of the protein family
@en
Diversity of the protein disul ...... members of the protein family
@nl
type
label
Diversity of the protein disul ...... members of the protein family
@ast
Diversity of the protein disul ...... members of the protein family
@en
Diversity of the protein disul ...... members of the protein family
@nl
prefLabel
Diversity of the protein disul ...... members of the protein family
@ast
Diversity of the protein disul ...... members of the protein family
@en
Diversity of the protein disul ...... members of the protein family
@nl
P2093
P3181
P1476
Diversity of the protein disul ...... members of the protein family
@en
P2093
Barbara Knoblach
Marek Michalak
Marianne Sommarin
Roya Khosravi-Far
P304
P3181
P356
10.1016/J.YMPEV.2005.04.002
P407
P577
2005-09-01T00:00:00Z