Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor
about
Cloning from the thyroid of a protein related to actin binding protein that is recognized by Graves disease immunoglobulinsInvolvement of G protein-coupled receptor kinase 5 in homologous desensitization of the thyrotropin receptorTwo-subunit structure of the human thyrotropin receptorThymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymusBioassays for TSH Receptor Autoantibodies, from FRTL-5 Cells to TSH Receptor-LH/CG Receptor Chimeras: The Contribution of Leonard D. KohnReview and hypothesis: does Graves' disease develop in non-human great apes?Graves' ophthalmopathyCloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodiesTSH signalling and cancer.Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at WorkHormone interactions to Leu-rich repeats in the gonadotropin receptors. I. Analysis of Leu-rich repeats of human luteinizing hormone/chorionic gonadotropin receptor and follicle-stimulating hormone receptor.Expression patterns of glucose transporter-1 gene and thyroid specific genes in human papillary thyroid carcinoma.Thyrotropin (TSH) receptor residue E251 in the extracellular leucine-rich repeat domain is critical for linking TSH binding to receptor activationInfluence of the TSH receptor gene on susceptibility to Graves' disease and Graves' ophthalmopathy.Thyrotropin receptor-associated diseases: from adenomata to Graves diseaseThe genetics of the thyroid stimulating hormone receptor: history and relevanceNovel information on the epitope of an inverse agonist monoclonal antibody provides insight into the structure of the TSH receptorUnlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices.Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice.Historical note: many steps led to the 'discovery' of thyroid-stimulating hormone.Evidence that the thyroid-stimulating hormone (TSH) receptor transmembrane domain influences kinetics of TSH binding to the receptor ectodomain.The TSH receptor reveals itself.Crystal structure of a TSH receptor monoclonal antibody: insight into Graves' disease pathogenesis.Recent developments in the investigation of thyroid regulation and thyroid carcinogenesisRelationship between thyrotropin receptor hinge region proteolytic posttranslational modification and receptor physiological functionThe coexistence of a novel inactivating mutant thyrotropin receptor allele with two thyroid peroxidase mutations: a genotype-phenotype correlationMolecular basis for the autoreactivity against thyroid stimulating hormone receptor.Autoimmune thyroiditis and targeted anti-T cell immunotherapy in man.Rapid bioassay for detection of thyroid-stimulating antibodies using cyclic adenosine monophosphate-gated calcium channel and aequorinHuman longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolismDeleting the Redundant TSH Receptor C-Peptide Region Permits Generation of the Conformationally Intact Extracellular Domain by Insect Cells.Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity.Thyroid dermopathy-a diagnostic clue of hidden hyperthyroidism.The thyrotropin receptor hinge region as a surrogate ligand: identification of loci contributing to the coupling of thyrotropin binding and receptor activationThe thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction.Identification of key amino acid residues in a thyrotropin receptor monoclonal antibody epitope provides insight into its inverse agonist and antagonist properties.TSH Receptor Cleavage Into Subunits and Shedding of the A-Subunit; A Molecular and Clinical Perspective.Insight into screening immunoglobulin gene combinatorial libraries in a phage display vector: a tale of two antibodies.Novel insights on thyroid-stimulating hormone receptor signal transduction.
P2860
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P2860
Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor
description
1989 nî lūn-bûn
@nan
1989 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Molecular cloning, sequence an ...... the human thyrotropin receptor
@ast
Molecular cloning, sequence an ...... the human thyrotropin receptor
@en
Molecular cloning, sequence an ...... the human thyrotropin receptor
@nl
type
label
Molecular cloning, sequence an ...... the human thyrotropin receptor
@ast
Molecular cloning, sequence an ...... the human thyrotropin receptor
@en
Molecular cloning, sequence an ...... the human thyrotropin receptor
@nl
prefLabel
Molecular cloning, sequence an ...... the human thyrotropin receptor
@ast
Molecular cloning, sequence an ...... the human thyrotropin receptor
@en
Molecular cloning, sequence an ...... the human thyrotropin receptor
@nl
P2093
P3181
P1476
Molecular cloning, sequence an ...... the human thyrotropin receptor
@en
P2093
P304
P3181
P356
10.1016/0006-291X(89)92727-7
P407
P577
1989-12-29T00:00:00Z